Du sökte efter: STEMCELL Technologies

Leverantör: STEMCELL Technologies

Beskrivning: Immunomagnetic isolation of untouched mouse naïve CD8+ T cells

Artikel nummer : (STMC09500)

Leverantör: STEMCELL Technologies

Beskrivning: Supplement for serum-free cell culture media.

UOM: 1 * 100 mL

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Leverantör: STEMCELL Technologies

Beskrivning: Immunomagnetic isolation of untouched mouse stem/progenitor cells

Artikel nummer : (STMC60038BT)

Leverantör: STEMCELL Technologies

Beskrivning: Rat monoclonal IgG2b antibody against mouse EPCR (CD201), biotin-conjugated.

UOM: 1 * 0,5 mL

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Leverantör: STEMCELL Technologies

Beskrivning: Platelet-derived growth factor (PDGF) is a dimeric glycoprotein consisting of two disulfide bridge-stabilized polypeptide chains, A and B, which are assembled as heterodimers (PDGF-AB) or homodimers (PDGF-AA and PDGF-BB) (Fretto <i>et al.</i>; Westermark and Heldin). PDGF signals through the receptor tyrosine kinases PDGFRalpha and PDGFRbeta. It has been shown that PDGF-induced migration involves signaling pathways involving MEK/ERK, EGFR, Src, and PI3K/AKT (Kim <i>et al.</i>). PDGF is a potent mitogen for cells of mesenchymal origin, such as fibroblasts, glial cells, and vascular smooth muscle cells. PDGF has been implicated in pathogenesis of atherosclerosis, glomerulonephritis, cancer, and in the contraction of vascular smooth muscle cells of rat aortic tissues (Fretto <i>et al.</i>; Sachinidis <i>et al.</i>). It has been suggested that PDGF-AA is an important autocrine regulator of vascular endothelial growth factor (VEGF) expression in non-small cell lung carcinomas (Shikada <i>et al.</i>). PDGF-AA also mediates proliferation of oligodendrocyte progenitor cells and oligodendrocyte lineage differentiation through the activation of extracellular signal-regulated kinases 1 and 2 (ERK1/2) (Hu <i>et al.</i>). PDGF-AA is commonly used to differentiate human pluripotent stem cell (hPSC)-derived neural progenitor cells into oligodendrocyte precursor cells (Piao <i>et al.</i>).

Artikel nummer : (STMC03818)

Leverantör: STEMCELL Technologies

Beskrivning: Semi-solid methylcellulose-based medium for selection and cloning of cells.

UOM: 1 * 45 mL

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Leverantör: STEMCELL Technologies

Beskrivning: Mouse monoclonal IgG1 antibody against human CD34, Alexa Fluor® 488-conjugated.

Leverantör: STEMCELL Technologies

Beskrivning: Human Interleukin 4 (IL-4) is important for immune responses to helminth infection as well as in allergic responses (Olpihant <i>et al.</i>). The IL-4 receptor consists of a heterodimer of IL-4Ra and common gamma chain. IL-4 receptor engagement leads to the activation of JAK1/3 and the recruitment of STAT6 and IRS1/2 (Nelms <i>et al.</i>). IL-4 drives immunoglobulin class switching in B cells (to IgE, IgG4), mast cell hyperplasia, mucus production, and the differentiation of naïve T cells into Th2 cells, which produce IL-4, IL-5, IL-10, and IL-13 (Bao <i>et al.</i>; Nelms <i>et al.</i>; Olpihant <i>et al.</i>). In addition to Th2 cells, IL-4 is produced by CD4+ NK T cells, γ/δ T cells, activated basophils, eosinophils, and mast cells. Human IL-4 does not cross-react with mouse cells (Park <i>et al.</i>).

Leverantör: STEMCELL Technologies

Beskrivning: Rat monoclonal IgG2a antibody against mouse CD62L (L-selectin), PerCP-Cy5.5-conjugated.

Artikel nummer : (STMC60020AD)

Leverantör: STEMCELL Technologies

Beskrivning: Rat monoclonal IgM antibody against mouse CD49b (integrin α2), Alexa Fluor® 488-conjugated.

UOM: 1 * 25 µG

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Artikel nummer : (STMC60137)

Leverantör: STEMCELL Technologies

Beskrivning: Mouse monoclonal IgG1 antibody against human MUC1 (CD227), unconjugated.

UOM: 1 * 200 µG

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Leverantör: STEMCELL Technologies

Beskrivning: Noggin binds to and antagonizes bone morphogenetic protein (BMP) ligands of the transforming growth factor beta (TGF-β) family. Noggin supports maintenance of undifferentiated human embryonic stem cells cultured in mouse embryonic fibroblast (MEF)-conditioned medium (Chaturvedi <i>et al.</i>), and promotes dopaminergic differentiation of embryonic stem cells and subsequent survival of dopamine neurons (Chiba <i>et al.</i>). Noggin is essential for development of ectodermal structures including neural tube, tooth, hair follicle, and eye, as well as patterning of mesodermal somites and skeletal structures. It also influences chondrogenesis, osteogenesis, and joint formation (Krause <i>et al.</i>).

Leverantör: STEMCELL Technologies

Beskrivning: Rat monoclonal IgG2b antibody against mouse Gr-1 (Ly-6G/Ly-6C), PE-conjugated.

Leverantör: STEMCELL Technologies

Beskrivning: Rat monoclonal IgG2a antibody against mouse Ly-6G, PE-conjugated.

Leverantör: STEMCELL Technologies

Beskrivning: For digestion of the extracellular matrix of cartilage.

Leverantör: STEMCELL Technologies

Beskrivning: Rat monoclonal IgM, kappa isotype control antibody, unconjugated.