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Product Image-ENZOALX420035M005

Apoptosis activator 2 ≥98%

Leverantör: ENZO LIFE SCIENCES AG
Beskrivning: Apoptosis inducer.

New Product

Image Unavailable-A1895-25G

Aurintricarboxylic acid ≥85%, pulver, Practical grade for titration, Sigma-Aldrich®

Leverantör: SIGMA-ALDRICH MICROSCOPY
Beskrivning: Readily polymerizes in aqueous solution, forming a stable free radical that inhibits protein-nucleic acid interactions. It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase Cγ in PC12 cells. Inhibits apoptosis. It prevents down-regulation of Ca²⁺ -impermeable GluR2 receptors and inhibits calpain, a Ca²⁺ -activated protease that is activated during apoptosis.

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Aluminon ACS, Sigma-Aldrich®

Leverantör: SIGMA-ALDRICH MICROSCOPY
Beskrivning: Reagent for aluminium. Aurintricarboxylic acid readily polymerises in aqueous solution, forming a stable free radical that inhibits protein-nucleic acid interactions. It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase C in PC12 cells. Aurintricarboxylic acid inhibits apoptosis in many cell types. Its neuroprotective effect, perhaps due to its ability to prevent down-regulation of Ca²⁺ impermeable GluR2 receptors or to its ability to inhibit calpain, a Ca²⁺-activated protease that is activated during apoptosis.

Image Unavailable-BOSSBS-0058R-A488

Anti-APAF1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Artikel nummer : (BOSSBS-0058R-A488)
Leverantör: Bioss
Beskrivning: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
UOM: 1 * 100 µl
Product Image-30061.

Apoptosis and necrosis quantitation kits

Leverantör: Biotium
Beskrivning: Apoptosis and necrosis are two processes by which cells die. Apoptosis is an active, regulated disassembly of the cell from within. During apoptosis, phosphatidylserine is translocated from the inner to the outer surface of the cell, allowing the dying cell to be engulfed by phagocytic cells. Annexin V is a 35 kD Ca2+-dependent phospholipid binding protein with a high affinity for phosphatidylserine.

Image Unavailable-BOSSBS-0058R-A750

Anti-APAF1 (CT) Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel nummer : (BOSSBS-0058R-A750)
Leverantör: Bioss
Beskrivning: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0059R-A680

Anti-APAF1 (NT) Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel nummer : (BOSSBS-0059R-A680)
Leverantör: Bioss
Beskrivning: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8869R-A555

Anti-ITPR1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Artikel nummer : (BOSSBS-8869R-A555)
Leverantör: Bioss
Beskrivning: Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8869R-A647

Anti-ITPR1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Artikel nummer : (BOSSBS-8869R-A647)
Leverantör: Bioss
Beskrivning: Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0059R-CY5.5

Anti-APAF1 Rabbit Polyclonal Antibody (Cy5.5®)

Artikel nummer : (BOSSBS-0059R-CY5.5)
Leverantör: Bioss
Beskrivning: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0049R-FITC

Anti-CASP9 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Artikel nummer : (BOSSBS-0049R-FITC)
Leverantör: Bioss
Beskrivning: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0049R-A350

Anti-CASP9 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Artikel nummer : (BOSSBS-0049R-A350)
Leverantör: Bioss
Beskrivning: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0059R-A488

Anti-APAF1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Artikel nummer : (BOSSBS-0059R-A488)
Leverantör: Bioss
Beskrivning: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0059R-FITC

Anti-APAF1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Artikel nummer : (BOSSBS-0059R-FITC)
Leverantör: Bioss
Beskrivning: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1870R-A680

Anti-PEG3 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel nummer : (BOSSBS-1870R-A680)
Leverantör: Bioss
Beskrivning: Induces apoptosis in cooperation with SIAH1A. Acts as a mediator between p53/TP53 and BAX in a neuronal death pathway that is activated by DNA damage. Acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B (By similarity). Possesses a tumor suppressing activity in glioma cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0049R-A680

Anti-CASP9 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel nummer : (BOSSBS-0049R-A680)
Leverantör: Bioss
Beskrivning: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
UOM: 1 * 100 µl
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Lager för denna produkt är begränsat, men kan vara tillgänglig i ett lager nära dig. Se till att du är inloggad på hemsidan så att tillgängligt lager kan visas. Om call fortfarande visas och du behöver hjälp, ring oss på 08-621 34 20.
Lager för denna produkt är begränsat, men kan vara tillgänglig i ett lager nära dig. Se till att du är inloggad på hemsidan så att tillgängligt lager kan visas. Om call fortfarande visas och du behöver hjälp, ring oss på 08-621 34 20.
VWR International AB säljer bara etanol till skattebefriade kunder. Denna produkt ä reglerad enligt svensk lagstiftning. Om ytterligare information krävs av dig kommer du att kontaktas via e-post.
VWR International AB säljer bara etanol till skattebefriade kunder.
Denna produkt ä reglerad enligt svensk lagstiftning. Om ytterligare information krävs av dig kommer du att kontaktas via email.
Produkten har blockerats av din organisation. Vänligen kontakta din inköpsavdelning för mer information.
Lösenordet och säkerhetsfrågan associerade med ditt Kundnummer har gått ut. Vänligen ändra ditt lösenord och din säkerhetsfråga.
Denna produkt är inte längre tillgänglig. Alternativ kan vara tillgängliga genom att söka med VWR art.nr ovan. Om du behöver ytterligare hjälp, ring VWR Kundservice på 08-621 34 20.
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