Anti-CD45.2 Mouse Monoclonal Antibody [clone: 104] (Biotin)

Leverantör: STEMCELL Technologies
60118BT 60118BT.1
STMC60118BTEA 1819 SEK
STMC60118BT STMC60118BT.1
Anti-CD45.2 Mouse Monoclonal Antibody [clone: 104] (Biotin)
Antikroppar
Mouse monoclonal IgG2a antibody against mouse CD45.2, biotin-conjugated.

  • Granulocytes
  • Subsets
  • Hematopoietic Stem
  • Progenitor cells
  • Lymphocytes
  • Myeloid cells

This monoclonal antibody (clone 104) reacts with mouse alloantigen cluster of differentiation 45.2 (CD45.2), also known as Ly5.2 and leukocyte common antigen, a 180 -240 kD type I transmembrane glycoprotein. CD45.2 is an allelic form of CD45 expressed by all hematopoietic cells except mature erythrocytes and platelets in mouse strains 129, A, AKR, BALB/c, C3H/He, C57BL/6, C58, CBA, DBA/1, and DBA/2. Use this recombinant monoclonal antibody in applications requiring detection of CD45.2, such as flow cytometry (FC). This antibody clone has been verified for purity assessment of cells isolated with EasySep™ Mouse CD45 Positive Selection Kit (Catalog #18945) or EasySep™ Mouse TIL (CD45) Positive Selection Kit (Catalog #100-0350). Clone 104 does not react with leukocytes that express the CD45.1 alloantigen. CD45 is a member of the protein tyrosine phosphatase (PTP) family and contains two catalytic domains in the intracellular (COOH) domain, which regulate cellular signaling. The extracellular domains are highly variable due to alternative splicing among exons 4, 5, and 6 as well as differential glycosylation. These CD45 isoforms correlate to specific cell types as well as specific activation and maturation states of immune cells. This monoclonal antibody has been used extensively in adoptive cell transfer and bone marrow transplantation studies in mice, allowing for the differentiation of CD45.2+ and CD45.1+ cells.

Observera: Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').

Type:
Antigen: CD45.2
Clonality: Monoclonal
Clone: 104
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG2a kappa
Reactivity: Mouse
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