Tacrolimus ≥98%, crystalline powder
Leverantör: ENZO LIFE SCIENCES AG
|
Fara
|
Synonyms:
FR900506, Fujimycin, (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone
Immunosuppressant.
Immunosuppressant that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. Shown to inhibit the activity of FK506 binding protein and to inhibit the Ca²⁺-dependent phosphatase and protein phosphatase 2B (PP2B; calcineurin). Activates NF-κB through phosphorylation and degradation of IκBα.
Soluble in DMSO, 100% ethanol, methanol, ethyl acetate or acetone; insoluble in water.
Formel:
C₄₄H₆₉NO₁₂ MW: 804,031 g/mol Storage Temperature: Frys |
MDL Number:
MFCD00869853 CAS nummer: 104987-11-3 UN: 2811 ADR: 6.1,III Merck Index: 14,09025 |
Specifikation testresultat
Purity | ≥98% (Assay) |
Source | Isolated from Streptomyces tsukubaensi |
Learn more
About VWR
Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...