Tacrolimus ≥98%, crystalline powder

Leverantör: ENZO LIFE SCIENCES AG
Fara

Synonyms: FR900506, Fujimycin, (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone

ALX380008M001 ALX380008M005 ALX380008M025
ENZOALX380008M001EA 615 SEK
ENZOALX380008M001 ENZOALX380008M005 ENZOALX380008M025
Tacrolimus ≥98%, crystalline powder
Tacrolimus

Immunosuppressant.


Immunosuppressant that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. Shown to inhibit the activity of FK506 binding protein and to inhibit the Ca²⁺-dependent phosphatase and protein phosphatase 2B (PP2B; calcineurin). Activates NF-κB through phosphorylation and degradation of IκBα.


Soluble in DMSO, 100% ethanol, methanol, ethyl acetate or acetone; insoluble in water.

Formel: C₄₄H₆₉NO₁₂
MW: 804,031 g/mol
Storage Temperature: Frys
MDL Number: MFCD00869853
CAS nummer: 104987-11-3
UN: 2811
ADR: 6.1,III
Merck Index: 14,09025

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Specifikation testresultat

Purity ≥98% (Assay)
Source Isolated from Streptomyces tsukubaensi

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