Du sökte efter: ENZO LIFE SCIENCES AG

Artikel nummer : (ENZOBMLSA4620100)

Leverantör: ENZO LIFE SCIENCES AG

Beskrivning: ACE1 (angiotensin converting enzyme-1, ACE) is a key regulator of blood pressure.

UOM: 1 * 100 µG

New Product Sale

Leverantör: ENZO LIFE SCIENCES AG

Beskrivning: Heme Oxygenase-1 (HO-1) also known as Hsp32, is the inducible isoform of heme oxygenase that catalyzes the NADPH, oxygen, and cytochrome P450 reductase dependent oxidation of heme to carbon monoxide, ferrous iron and biliverdin which is rapidly reduced to bilirubin. These products of the HO reaction have important physiological effects: carbon monoxide is a potent vasodilator and has been implicated to be a physiological regulator of cGMP and vascular tone; biliverdin and its product bilirubin are potent antioxidants; "free" iron increases oxidative stress and regulates the expression of many mRNAs (e.g., DCT-1, ferritin and transferring receptor) by affecting the conformation of iron regulatory protein (IRP)-1 and its binding to iron regulatory elements (IREs) in the 5'- or 3'- UTRs of the mRNAs. To date, three identified heme oxygenase isoforms are part of the HO system that catalyze heme into biliverdin and carbon monoxide. These are inducible HO-1 or Hsp32, constitutive HO-2 that is abundant in the brain and testis, and HO-3 which is related to HO-2 but is the product of a different gene. The HO system is the rate-limiting step in heme degradation and HO activity decreases the levels of heme which is a well known potent catalyst of lipid peroxidation and oxygen radical formation.

New Product

Leverantör: ENZO LIFE SCIENCES AG

Beskrivning: Produced in <i>E. coli</i>.

New Product

Artikel nummer : (ENZOALX801010L001)

Leverantör: ENZO LIFE SCIENCES AG

Beskrivning: Host: Mouse, Isotype: IgG1

UOM: 1 * 1 mL

New Product Sale

Artikel nummer : (ENZOALX801021C250)

Leverantör: ENZO LIFE SCIENCES AG

Beskrivning: Host: Rat, Isotype: IgG2a

UOM: 1 * 250 µG

New Product Sale

Leverantör: ENZO LIFE SCIENCES AG

Beskrivning: HIF-1α activator.

New Product

Leverantör: ENZO LIFE SCIENCES AG

Beskrivning: Most efficient spin trap for the <i>in vitro</i> and <i>in vivo</i> detection of O-, N-, S-, and C-centered free radicals.

New Product

Artikel nummer : (ENZOALX850018KI01)

Leverantör: ENZO LIFE SCIENCES AG

Beskrivning: Induces apoptosis in a concentration range of 1 to100 ng/ml if applied with the cross-linking enhancer.

UOM: 1 * 1 SET

New Product Sale

Artikel nummer : (ENZOADI905781100)

Leverantör: ENZO LIFE SCIENCES AG

Beskrivning: Septin 5 (Sept5/CDCrel-1) is a member of the Septin family of cytoskeletal GTPases. Septin 5 expression is primarily associated with synaptic vesicles in cells of the nervous system where it acts to inhibit exocytosis, although it has also been characterized as an inhibitor of aggregation and release of storage granules in platelets. Phosphorylation of Septin 5 at Ser17 by Cdk5-p35 has been shown to mediate the interaction of Septin 5 with the SNARE protein Syntaxin-1A, regulating neurotransmitter release. Targeted disruption of the Septin 5 gene in mice failed to produce an obvious neurological phenotype, indicating its loss may be overcome by functional redundancy of other septins. Septin 5 is one of several Parkin (an E3 ubiquitin ligase) associated substrates whose accumulation results in cellular toxicity related to the onset of autosomal recessive Parkinson Disease.

UOM: 1 * 100 µG

New Product Sale

Artikel nummer : (ENZOBMLP1320500)

Leverantör: ENZO LIFE SCIENCES AG

Beskrivning: Fluorogenic substrate for TACE (ADAM17) (between Ala-Val), as well as MMP-3, MMP-7, MMP-12, and MMP-17, but not for ADAM19, MMP-13, nor MMP-14. Similar substrates are also cleaved by ADAM10, ADAM8 and ADAM9, and MMP-1, -2, and -9. This quenched substrate is useful for TACE inhibitor screening and kinetic analysis. Ex: 328 nm, Em: 393 nm, although the following Ex/Em have been used: 320-340/400-420. Also available: OMNIMMP® Fluorogenic Control peptide (BML-P127).

UOM: 1 * 0,5 mg

New Product Sale

Leverantör: ENZO LIFE SCIENCES AG

Beskrivning: Produced in <i>E. coli</i>.

New Product

Leverantör: ENZO LIFE SCIENCES AG

Beskrivning: Inhibits ATP-sensitive K+ channels.

New Product

Leverantör: ENZO LIFE SCIENCES AG

Beskrivning: Inhibits α-mannosidase. Inhibits asparagine-linked oligosaccharide processing. Immunomodulator.

New Product

Artikel nummer : (ENZOBMLEI1640005)

Leverantör: ENZO LIFE SCIENCES AG

Beskrivning: COX inhibitor

UOM: 1 * 5 g

New Product Sale

Leverantör: ENZO LIFE SCIENCES AG

Beskrivning: Beneficial effects in cardiovascular diseases and inflammation.

New Product

Leverantör: ENZO LIFE SCIENCES AG

Beskrivning: Immunosuppressant

New Product