Indirubin ≥98% (by 1H-NMR, HPLC)
Leverantör: ENZO LIFE SCIENCES AG
Synonyms:
Indigo Red, [2,3'-Biindolinylidene]-2',3-dione
ALX270361M001
ALX270361M005
ENZOALX270361M001EA
945
SEK
ENZOALX270361M001
ENZOALX270361M005
Indirubin ≥98% (by 1H-NMR, HPLC)
Indirubin
Inhibitor of CDK and GSK
Inhibitor of cyclin-dependent kinases (CDK1/cyclin B (IC50=10µM), CDK2/cyclin A (IC50=2.2µM), CDK2/cyclin E (IC50=7.5µM), CDK4/cyclin D1 (IC50=12µM), CDK5/p35 (IC50=5.5µM)) and of GSK-3beta (IC50=600nM). Inhibits inflammatory reaction in delayed-type hypersensitivity in mice. Ligand of human aryl hydrocarbon receptor. Exhibits anti-cancer activity.
Synthetic.
Formel:
C₁₆H₁₀N₂O₂ MW: 262,27 g/mol |
MDL Number:
MFCD00221745 CAS nummer: 479-41-4 |
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