Fasudil dihydrochloride ≥98%
Leverantör: ENZO LIFE SCIENCES AG
Synonyms:
1-(5-Isoquinolinesulphonyl)homopiperazine dihydrochloride salt, HA-1077 dihydrochloride salt
Inhibits Rho kinase (ROCK; Ki=0.33μM). Selective protein kinase A and G inhibitor (both Ki’s = 1.6μM). Inhibits agonist-induced activation of NADPH oxidase in human neutrophils (IC50=15μM). Inhibitor of myosin light chain kinase and Ca2+/calmodulin-dependent protein kinase II. Inhibits translocation of PKCβI, PKCβII and PKCζ. Cell permeable Ca2+ antagonist with antivasospastic properties.
- Rho kinase (ROCK) inhibitor
White to off-white solid.
Soluble in water (>20mg/ml), methanol or DMSO.
Formel:
C₁₄H₁₇N₃O₂S·2HCl MW: 364,29 g/mol Storage Temperature: Frys |
MDL Number:
MFCD00153805 CAS nummer: 203911-27-7 |
Learn more
About VWR
Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...