Anti-SILV Mouse Monoclonal Antibody (CF568) [clone: PMEL/783]

Leverantör: Biotium

BNC680783-500 BNC680783-100
BNC680783-500EA 6150 SEK
BNC680783-500 BNC680783-100
Anti-SILV Mouse Monoclonal Antibody (CF568) [clone: PMEL/783]
Antikroppar
Cytotoxic T lymphocytes (CTL's) recognize melanoma-associated antigens, which belong to three main groups. These groups include tumor-associated testis-specific antigens, melanocyte differentiation antigens and mutated or aberrantly expressed antigens, which are routinely used as markers to identify melanomas based on their binding to specific monoclonal antibodies. gp100, also designated ME20-M, ME20-S and PMEL 17, is classified as a melanocyte differentiation antigen and is expressed at low levels in normal cell lines and tissues, but is upregulated in melanocytes. gp100 is a highly glycosylated protein. It is also the product of proteolytic cleavage, which results in a secreted protein.

Type: Primary
Antigen: SILV
Clonality: Monoclonal
Clone: PMEL/783
Conjugation: CF568
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human
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