Anti-CD66 molecule Mouse Monoclonal Antibody (CF647) [clone: C66/195]

Leverantör: Biotium

BNC470195-500 BNC470195-100
BNC470195-500EA 6150 SEK
BNC470195-500 BNC470195-100
Anti-CD66 molecule Mouse Monoclonal Antibody (CF647) [clone: C66/195]
Antikroppar
This antibody recognizes proteins of 80-200 kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb reacts with nonspecific cross-reacting antigen (NCA) and shows a cross-reaction with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA ) from pleural mesotheliomas (rarely or weakly CEA ). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.

Type: Primary
Antigen: CD66 molecule
Clonality: Monoclonal
Clone: C66/195
Conjugation: CF647
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human, Monkey
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