Isolating individual or groups, the cloning cylinders surround target cells for identical reproduction. Glass or plastic may be dipped into sterile grease before pressing down in order to create the best seal. With a wider bottom, the tapered styles promote a tighter seal. Glass models that are glazed on both ends are suitable for use in disinfectant procedures. Providing a homogenous culture of cells, the cloning cylinders allow more accurate comparisons for research.