Du sökte efter: torc1

Artikel nummer : (ABCAAB70823-100)

Leverantör: Abcam

Beskrivning: Rabbit polyclonal to TORC1.

UOM: 1 * 100 µl

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Artikel nummer : (BWRLMB0104)

Leverantör: Bioworld Technology

Beskrivning: Synthetic peptide, corresponding to the N-terminus of Human TORC1.

UOM: 1 * 100 µG

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Artikel nummer : (ABCAAB92477-100)

Leverantör: Abcam

Beskrivning: Rabbit monoclonal [EPR3382] to TORC1.

UOM: 1 * 100 µl

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Artikel nummer : (ABCAAB109736-100)

Leverantör: Abcam

Beskrivning: Anti-TORC1 Rabbit Monoclonal Antibody [clone: EPR3381(2)]

UOM: 1 * 100 µl

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Artikel nummer : (ABCAAB264144-100UL)

Leverantör: Abcam

Beskrivning: Rabbit polyclonal to TORC1.

UOM: 1 * 100 µl

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Artikel nummer : (BWRLMB0169)

Leverantör: Bioworld Technology

Beskrivning: Recombinant full length Human TORC1.

UOM: 1 * 100 µG

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Leverantör: Abcam

Beskrivning: Rabbit monoclonal [EPR3381(2)] to TORC1 - BSA and Azide free.

Leverantör: Abcam

Beskrivning: Rabbit monoclonal [EPR3382] to TORC1 - BSA and Azide free.

Artikel nummer : (ANTIA91995-100)

Leverantör: ANTIBODIES.COM

Beskrivning: Anti-TORC1 Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

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Artikel nummer : (BSBTPA1987)

Leverantör: Boster Bio

Beskrivning: Rabbit IgG polyclonal antibody for CREB-regulated transcription coactivator 1 (CRTC1) detection. Tested with WB in Human; Mouse; Rat.

UOM: 1 * 0,1 mg

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Artikel nummer : (BOSSBS-3453R-A750)

Leverantör: Bioss

Beskrivning: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukaemia virus type 1 (HTLV-1) long terminal repeats (LTR). In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses. May be required for dendritic growth of developing cortical neurons (By similarity). In concert with SIK1, regulates the light-induced entrainment of the circadian clock. In response to light stimulus, coactivates the CREB-mediated transcription of PER1 which plays an important role in the photic entrainment of the circadian clock.

UOM: 1 * 100 µl

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Artikel nummer : (BOSSBS-3453R-A680)

Leverantör: Bioss

Beskrivning: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukaemia virus type 1 (HTLV-1) long terminal repeats (LTR). In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses. May be required for dendritic growth of developing cortical neurons (By similarity). In concert with SIK1, regulates the light-induced entrainment of the circadian clock. In response to light stimulus, coactivates the CREB-mediated transcription of PER1 which plays an important role in the photic entrainment of the circadian clock.

UOM: 1 * 100 µl

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Artikel nummer : (USBI144391)

Leverantör: US Biological

Beskrivning: Anti-CRTC1 Rabbit Polyclonal Antibody

UOM: 1 * 100 µG

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Artikel nummer : (USBI143214)

Leverantör: US Biological

Beskrivning: Anti-CRTC1 Mouse Monoclonal Antibody [clone: 13k87]

UOM: 1 * 100 µl

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Artikel nummer : (BOSSBS-6252R-CY5)

Leverantör: Bioss

Beskrivning: Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, gluconeogenesis and lipogenesis regulation, muscle growth and differentiation and tumor suppression. Phosphorylates HDAC4, HDAC5, PPME1, SREBF1, CRTC1/TORC1 and CRTC2/TORC2. Acts as a tumor suppressor and plays a key role in p53/TP53-dependent anoikis, a type of apoptosis triggered by cell detachment: required for phosphorylation of p53/TP53 in response to loss of adhesion and is able to suppress metastasis. Part of a sodium-sensing signaling network, probably by mediating phosphorylation of PPME1: following increases in intracellular sodium, SIK1 is activated by CaMK1 and phosphorylates PPME1 subunit of protein phosphatase 2A (PP2A), leading to dephosphorylation of sodium/potassium-transporting ATPase ATP1A1 and subsequent increase activity of ATP1A1. Acts as a regulator of muscle cells by phosphorylating and inhibiting class II histone deacetylases HDAC4 and HDAC5, leading to promote expression of MEF2 target genes in myocytes. Also required during cardiomyogenesis by regulating the exit of cardiomyoblasts from the cell cycle via down-regulation of CDKN1C/p57Kip2. Acts as a regulator of hepatic gluconeogenesis by phosphorylating and repressing the CREB-specific coactivators CRTC1/TORC1 and CRTC2/TORC2, leading to inhibit CREB activity. Also regulates hepatic lipogenesis by phosphorylating and inhibiting SREBF1. In concert with CRTC1/TORC1, regulates the light-induced entrainment of the circadian clock by attenuating PER1 induction; represses CREB-mediated transcription of PER1 by phosphorylating and deactivating CRTC1/TORC1 (By similarity).

UOM: 1 * 100 µl

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Artikel nummer : (BOSSBS-6252R)

Leverantör: Bioss

Beskrivning: Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, gluconeogenesis and lipogenesis regulation, muscle growth and differentiation and tumor suppression. Phosphorylates HDAC4, HDAC5, PPME1, SREBF1, CRTC1/TORC1 and CRTC2/TORC2. Acts as a tumor suppressor and plays a key role in p53/TP53-dependent anoikis, a type of apoptosis triggered by cell detachment: required for phosphorylation of p53/TP53 in response to loss of adhesion and is able to suppress metastasis. Part of a sodium-sensing signaling network, probably by mediating phosphorylation of PPME1: following increases in intracellular sodium, SIK1 is activated by CaMK1 and phosphorylates PPME1 subunit of protein phosphatase 2A (PP2A), leading to dephosphorylation of sodium/potassium-transporting ATPase ATP1A1 and subsequent increase activity of ATP1A1. Acts as a regulator of muscle cells by phosphorylating and inhibiting class II histone deacetylases HDAC4 and HDAC5, leading to promote expression of MEF2 target genes in myocytes. Also required during cardiomyogenesis by regulating the exit of cardiomyoblasts from the cell cycle via down-regulation of CDKN1C/p57Kip2. Acts as a regulator of hepatic gluconeogenesis by phosphorylating and repressing the CREB-specific coactivators CRTC1/TORC1 and CRTC2/TORC2, leading to inhibit CREB activity. Also regulates hepatic lipogenesis by phosphorylating and inhibiting SREBF1. In concert with CRTC1/TORC1, regulates the light-induced entrainment of the circadian clock by attenuating PER1 induction; represses CREB-mediated transcription of PER1 by phosphorylating and deactivating CRTC1/TORC1 (By similarity).

UOM: 1 * 100 µl

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