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Artikel nummer : (BSENS-077-100)
Leverantör: Biosensis
Beskrivning: Beta-synuclein is a non-amyloid component of senile plaques found in Alzheimer disease. It could act as a regulator of SNCA aggregation. It protects neurons from staurosporine and 6 hydroxy dopamine -stimulated capspase activation in a p53-dependent manner. It localises to the cytoplasm and it is predominantly expressed in the brain where it is most concentrated in presynaptic nerve terminals. This protein is phosphorylated. This protein is also associated with the disease Brain iron accumulation type 1 (NBIA1).
UOM: 1 * 100 µG


Artikel nummer : (BOSSBS-0738R-CY3)
Leverantör: Bioss
Beskrivning: Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the inhibition of CASP3, CASP7 and CASP9, as well as by its E3 ubiquitin-protein ligase activity. As it is a weak caspase inhibitor, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival. May contribute to caspase inhibition, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions. Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits CASP3 and proteolytic activation of pro-CASP9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis. Isoform 2 protects against natural killer (NK) cell killing whereas isoform 1 augments killing.
UOM: 1 * 100 µl


Artikel nummer : (BOSSBS-0738R-CY5.5)
Leverantör: Bioss
Beskrivning: Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the inhibition of CASP3, CASP7 and CASP9, as well as by its E3 ubiquitin-protein ligase activity. As it is a weak caspase inhibitor, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival. May contribute to caspase inhibition, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions. Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits CASP3 and proteolytic activation of pro-CASP9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis. Isoform 2 protects against natural killer (NK) cell killing whereas isoform 1 augments killing.
UOM: 1 * 100 µl


Artikel nummer : (BOSSBS-0738R-A350)
Leverantör: Bioss
Beskrivning: Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the inhibition of CASP3, CASP7 and CASP9, as well as by its E3 ubiquitin-protein ligase activity. As it is a weak caspase inhibitor, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival. May contribute to caspase inhibition, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions. Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits CASP3 and proteolytic activation of pro-CASP9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis. Isoform 2 protects against natural killer (NK) cell killing whereas isoform 1 augments killing.
UOM: 1 * 100 µl


Artikel nummer : (00025.)
Leverantör: Biotium
Beskrivning: Staurosporine is a potent apoptosis inducer.
UOM: 1 * 100 µG


Leverantör: MP Biomedicals
Beskrivning: Staurosporine is provided in a lyophilised form. It may be reconstituted by dissolving the lyophilised reagent in DMSO (5 mg/ml - clear, colourless solution), DMF, ethyl acetate (5 mg/ml - clear colourless solution) or methanol. Stock solutions should be further diluted with aqueous buffers just prior to use. Stability depends upon the quality of solvent used. The compound should be stored at −20 °C in the dark.

Artikel nummer : (AATB80050)
Leverantör: AAT BIOQUEST
Beskrivning: Staurosporine is widely used as a positive control for inducing apoptosis.
UOM: 1 * 100 µl


Artikel nummer : (J62837.MA)
Leverantör: Thermo Fisher Scientific
Beskrivning: Staurosporine ≥99%
UOM: 1 * 10 mg

Artikel nummer : (569396-100)
Leverantör: Merck Millipore (Calbiochem‎)
Beskrivning: InSolution™ Staurosporine, <i>Streptomyces sp</i>. is provided as a 1 mM (100 µg/214 µl) solution of Staurosporine in DMSO.
UOM: 1 * 100 µG


Artikel nummer : (HONCR1061-10MG)
Leverantör: Honeywell Chemicals
Beskrivning: Organic Standard, Staurosporine, Förpackningstyp: Glass Bottle
UOM: 1 * 10 mg


Leverantör: ENZO LIFE SCIENCES
Beskrivning: Inhibitor of a variety of serine/threonine and tyrosine kinases, like protein kinase C (PKC), cyclic AMP-dependent protein kinase (PKA), S6 kinase, Akt (protein kinase B; PKB), epidermal growth factor receptor (EGFR) tyrosine kinase activity and others including KDR, VEGFR, PDGFR, c-kit and other receptor tyrosine kinases. Potently inhibits FLT-3 kinase including mutant forms found in acute myeloid leukemia in vitro and in vivo. Apoptosis inducer. Showed broad antiproliferative activity against various tumor cell lines. Selectively inhibits T lymphocyte production of TNF-α. Upregulates endothelial nitric oxide synthase (eNOS; NOS III). Abrogates tumor angiogenesis in vivo.

New Product

Artikel nummer : (PRSI55-786)
Leverantör: ProSci Inc.
Beskrivning: Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.
UOM: 1 * 400 µl

New Product


Artikel nummer : (ABCAAB146588-100)
Leverantör: Abcam
Beskrivning: STAUROSPORINE (DMSO SOLUTION) 1 * 100 µG
UOM: 1 * 100 µG


Artikel nummer : (CAYM81590-1)
Leverantör: Cayman Chemical
Beskrivning: STAUROSPORINE 1 * 1 mg
UOM: 1 * 1 mg


Artikel nummer : (ABCAAB120056-100)
Leverantör: Abcam
Beskrivning: STAUROSPORINE 1 * 100 µG
UOM: 1 * 100 µG

Artikel nummer : (CAYM81590-500)
Leverantör: Cayman Chemical
Beskrivning: STAUROSPORINE 1 * 500 µG
UOM: 1 * 500 µG


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Lager för denna produkt är begränsat, men kan vara tillgänglig i ett lager nära dig. Se till att du är inloggad på hemsidan så att tillgängligt lager kan visas. Om call fortfarande visas och du behöver hjälp, ring oss på 08-621 34 20.
Lager för denna produkt är begränsat, men kan vara tillgänglig i ett lager nära dig. Se till att du är inloggad på hemsidan så att tillgängligt lager kan visas. Om call fortfarande visas och du behöver hjälp, ring oss på 08-621 34 20.
VWR International AB säljer bara etanol till skattebefriade kunder. Denna produkt ä reglerad enligt svensk lagstiftning. Om ytterligare information krävs av dig kommer du att kontaktas via e-post.
VWR International AB säljer bara etanol till skattebefriade kunder.
Denna produkt ä reglerad enligt svensk lagstiftning. Om ytterligare information krävs av dig kommer du att kontaktas via email.
Produkten har blockerats av din organisation. Vänligen kontakta din inköpsavdelning för mer information.
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Denna produkt är inte längre tillgänglig. Alternativ kan vara tillgängliga genom att söka med VWR art.nr ovan. Om du behöver ytterligare hjälp, ring VWR Kundservice på 08-621 34 20.
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