Du sökte efter: Progesterone

Artikel nummer : (PROONE9310)

Leverantör: LGC Standards PROMOCHEM

Beskrivning: Organic Standard, Progesterone 10 µg/ml in methanol, Förpackningstyp: Glass bottle

UOM: 1 * 10 mL

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Leverantör: ANTIBODIES.COM

Beskrivning: Mouse monoclonal (ABT-PR) antibody to Progesterone Receptor for IHC with samples derived from Human.

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Artikel nummer : (ANTIA95954-100)

Leverantör: ANTIBODIES.COM

Beskrivning: Rabbit polyclonal antibody to Progesterone Receptor for WB and ELISA with samples derived from Human.

UOM: 1 * 100 µG

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Artikel nummer : (ANTIA252798-100)

Leverantör: ANTIBODIES.COM

Beskrivning: Anti-Progesterone Receptor Mouse Monoclonal Antibody [clone: PR501]

UOM: 1 * 100 µG

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Artikel nummer : (ABNOPAB8201)

Leverantör: Abnova

Beskrivning: Sheep polyclonal antibody raised against 17 alpha-OH-Progesterone.

UOM: 1 * 1 mg

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Artikel nummer : (ANTIA94416-100)

Leverantör: ANTIBODIES.COM

Beskrivning: Rabbit polyclonal antibody to Progesterone Receptor for IHC, IF and ELISA with samples derived from Human, Mouse and Rat.

UOM: 1 * 100 µG

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Artikel nummer : (BIRBORB44472-0.1)

Leverantör: Biorbyt

Beskrivning: Anti-Progesterone Mouse Monoclonal Antibody

UOM: 1 * 0,1 mg

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Artikel nummer : (PRSI33-519)

Leverantör: ProSci Inc.

Beskrivning: This mAb is specific for progesterone. It exhibits minimal cross reactivity with related compounds in ELISA. It reacts with progesterone-11a-HMS-BSA: 100%; 5-beta-Pregnane-3,20-dione: 48%; 5-alpha-Pregnane-3,20-dione: 26.4%; 17-alpha-Hydroxyprogesterone: 2.5%; 20-alpha-Hydroxyprogesterone: 0.04%. progesterone is a steroid hormone synthesised from the cholesterol derivative, pregnenolone, in the cortex of the adrenal gland. progesterone is secreted by the corpus luteum and acts to prepare the endometrium for the implantation of a fertilized egg. During pregnancy, it is secreted by the placenta to prevent spontaneous abortion and to stimulate the development of mammary tissue to produce milk. Thus, progesterone plays a central role in the reproductive events associated with the establishment and maintenance of pregnancy. Luteinized theca cells of normal ovary secrete progesterone. The determination of progesterone concentrations in the body fluids is of great value for endocrinological investigations in women. This mAb may prove useful in identification of ovarian tumors.

UOM: 1 * 100 µG

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Leverantör: ENZO LIFE SCIENCES

Beskrivning: GC UNC45 (general cell UNC45/unc45a) is an Hsp90 co-chaperone that has been shown to play a critical role in the chaperoning of myosin proteins as well as the progesterone receptor (PR). There are two known vertebrate isoforms of UNC45 that are functional orthologs of the C. elegans unc-45, an important protein in the development of organized body wall muscles. The vertebrate general cell form (GC UNC45/unc45a) is ubiquitously expressed, while the striated muscle-specific isoform (SM UNC45/unc45b) is found in cardiac and skeletal muscle. In vitro, GC UNC45 preferentially binds the Hsp90 beta isoform, and is specifically required for proper cellular distribution of Hsp90β but not Hsp90α.

Artikel nummer : (ANTIA252795-100)

Leverantör: ANTIBODIES.COM

Beskrivning: Anti-Progesterone Receptor Mouse Monoclonal Antibody [clone: PR484]

UOM: 1 * 100 µG

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Artikel nummer : (PRSI79-526)

Leverantör: ProSci Inc.

Beskrivning: Progesterone receptors (PRs) are nuclear hormone receptors of the NR3C class, which also includes mineralocorticoid, glucocorticoid and androgen receptors. They exist as homodimers coupled to Hsp90 or HMGB proteins, which are shed upon activation. The major signaling pathway used by Progesterone receptors is via direct DNA binding and transcriptional regulation of target genes. They can also signal by binding to other proteins, mainly with transcription factors such as NF-κB, AP-1 or STAT. Progesterone receptors are found in the female reproductive tract, mammary glands, brain and pituitary gland and receptor expression is induced by estrogen. Well established functions of Progesterone receptors include ovulation, implantation, mammary gland development and maintenance of pregnancy. In addition, Progesterone, signaling through the Progesterone receptor, increases the ventilatory response of the respiratory centers to carbon dioxide and decreases arterial and alveolar PCO2 in the luteal phase of the menstrual cycle and during pregnancy. The human gene encoding the Progesterone receptor has been localized to 11q22.

UOM: 1 * 100 µG

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Artikel nummer : (ANTIA249618-100)

Leverantör: ANTIBODIES.COM

Beskrivning: Mouse monoclonal [PR501] antibody to Progesterone Receptor for WB and IHC-P with samples derived from human.

UOM: 1 * 100 µG

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Leverantör: Biotium

Beskrivning: Recognizes a protein of 104 kDa-110 kDa, characterized as major vault protein (MVP). Vaults are large ribonucleoprotein particles (RNPs) present in all eukaryotic cells. They have a complex morphology, including several small molecules of RNA, but a single protein species. The MVP accounts for >70% of their mass. Their shape is reminiscent of the nucleopore central plug. Treatment of cells with estradiol increases the amount of MVP in nuclear extract. The hormone-dependent interaction of vaults with ER is prevented in vitro by sodium molybdate. Antibodies to estrogen, progesterone and glucocorticoid receptors are able to co-immunoprecipitate the MVP. MVP is overexpressed in many neoplastic tissues and cell lines. Expression of MVP predicts a poor response to chemotherapy.

Leverantör: Biotium

Beskrivning: Recognizes a protein of 110 kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin.This MAb is superb for staining of formalin/paraffin tissues.

Leverantör: Biotium

Beskrivning: Recognizes a protein of 110 kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin.This MAb is superb for staining of formalin/paraffin tissues.

Leverantör: Biotium

Beskrivning: Recognizes a protein of 110 kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin.This MAb is superb for staining of formalin/paraffin tissues.