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Malonyl coenzyme A lithium salt ≥90%

Leverantör: Cayman Chemical
Beskrivning: Malonyl-CoA is formed by acetyl-CoA carboxylase-mediated carboxylation of acetyl-CoA. Fatty acid synthase catalyzes the NADPH-dependent condensation of malonyl-CoA and acetyl-CoA to produce palmitate. Proliferating human cancer cells upregulate this fatty acid synthesis pathway as a strategy for survival. High levels of malonyl-CoA, achieved through fatty acid synthase inhibition, proposed to contribute to cancer cell apoptosis.

Image Unavailable-07441-10MG

Supelco® Organic Reference Standard, Malonyl-L-Carnitine Lithium Salt

Leverantör: Merck
Beskrivning: Organic Standard, Malonyl-ʟ-carnitine lithium salt

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Cerulenin ≥98%, crystalline solid

Leverantör: Cayman Chemical
Beskrivning: A number of tumor cells and cell lines have been observed to have highly upregulated expression and activity of fatty acid synthase (FAS). Inhibition of FAS by the irreversible inhibitor cerulenin leads to cytotoxicity and apoptosis in human cancer cell lines, an effect believed to be mediated by the accumulation of malonyl-coenzyme A in cells with an upregulated FAS pathway. Cerulenin also leads to profound weight loss and feeding inhibition in both high-fat diet wild type obese and leptin-deficient ob/ob mice.

Image Unavailable-BOSSBS-12952R-A680

Anti-Acetyl Coenzyme A Carboxylase beta Ser220 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel nummer : (BOSSBS-12952R-A680)
Leverantör: Bioss
Beskrivning: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyses the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12954R-A680

Anti-Acetyl Coenzyme A Carboxylase alpha Ser80 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel nummer : (BOSSBS-12954R-A680)
Leverantör: Bioss
Beskrivning: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyses the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12954R-A750

Anti-Acetyl Coenzyme A Carboxylase alpha Ser80 Rabbit Polyclonal Antibody (ALEXA FLUOR® 750)

Artikel nummer : (BOSSBS-12954R-A750)
Leverantör: Bioss
Beskrivning: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyses the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12952R-A750

Anti-Acetyl Coenzyme A Carboxylase beta Ser220 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel nummer : (BOSSBS-12952R-A750)
Leverantör: Bioss
Beskrivning: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyses the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
UOM: 1 * 100 µl
Image Unavailable-APOSBIC7401-100MG

Coenzyme A trilithium salt

Leverantör: Apollo Scientific
Beskrivning: Coenzyme A trilithium salt

Certifikat

Image Unavailable-CAYM10547-1

4-Pentynoyl-Coenzyme A (trifluoroacetate salt) ≥95%, lyophilised powder

Leverantör: Cayman Chemical
Beskrivning: 4-Pentynoyl-Coenzyme A (trifluoroacetate salt) ≥95%, lyophilised powder

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Coenzyme A sodium salt hydrate ≥95%

Leverantör: Cayman Chemical
Beskrivning: Coenzyme A (CoA) is an essential cofactor functioning as an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. About 4% of cellular enzymes utilize CoA as a substrate. It is synthesized from pantothenic acid in a five-step process that requires ATP. The pantothenate kinase step of the CoA biosynthetic pathway is identified as a target for the development of antibacterial compounds.

Image Unavailable-APOSBIA1091-50MG

Acetyl-Coenzyme A Trilithium Salt

Leverantör: Apollo Scientific
Beskrivning: Acetyl-Coenzyme A Trilithium Salt

Certifikat

Image Unavailable-8.22084.0100

L(+)-Lithium lactate för syntes, Sigma-Aldrich®

Leverantör: Merck
Beskrivning: L(+)-Lithium lactate för syntes, Sigma-Aldrich®

Säkerhetsdatablad

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Riboflavin 5'-monophosphate sodium salt hydrate

Leverantör: Cayman Chemical
Beskrivning: Riboflavin 5'-monophosphate (FMN) is a coenzyme that is tightly bound to enzymes catalysing oxidation and reduction reactions in a variety of biosynthetic pathways.

Image Unavailable-ENZOALX460003G010

Calcium pantothenate ≥98%

Artikel nummer : (ENZOALX460003G010)
Leverantör: ENZO LIFE SCIENCES AG
Beskrivning: Precursor for coenzyme A biosynthesis.
UOM: 1 * 10 g

New Product


Image Unavailable-55385-10MG

Supelco® Organic Reference Standard, 3-Phosphoshikimic acid lithium salt

Artikel nummer : (55385-10MG)
Leverantör: Merck
Beskrivning: Organic Standard, 3-Phosphoshikimic acid lithium salt
UOM: 1 * 10 mg
Image Unavailable-89921-10MG

Supelco® Organic Reference Standard, (±)-2,4-Dihydroxybutyric acid lithium salt

Leverantör: Merck
Beskrivning: Organic Standard, (±)-2,4-Dihydroxybutyric acid lithium salt

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Lager för denna produkt är begränsat, men kan vara tillgänglig i ett lager nära dig. Se till att du är inloggad på hemsidan så att tillgängligt lager kan visas. Om call fortfarande visas och du behöver hjälp, ring oss på 08-621 34 20.
VWR International AB säljer bara etanol till skattebefriade kunder. Denna produkt ä reglerad enligt svensk lagstiftning. Om ytterligare information krävs av dig kommer du att kontaktas via e-post.
VWR International AB säljer bara etanol till skattebefriade kunder.
Denna produkt ä reglerad enligt svensk lagstiftning. Om ytterligare information krävs av dig kommer du att kontaktas via email.
Produkten har blockerats av din organisation. Vänligen kontakta din inköpsavdelning för mer information.
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Denna produkt är inte längre tillgänglig. Alternativ kan vara tillgängliga genom att söka med VWR art.nr ovan. Om du behöver ytterligare hjälp, ring VWR Kundservice på 08-621 34 20.
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