Du sökte efter: 7-Bromobenzofuran-2-carboxylic+acid

Beskrivning: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates E3 ubiquitin ligase activity either through direct binding to substrates or by functioning as the essential RING domain subunit of larger E3 complexes. Triggers the ubiquitin-mediated degradation of many substrates, including proteins involved in transcription regulation (ELL2, MYB, POU2AF1, PML and RBBP8), a cell surface receptor (DCC), the cell-surface receptor-type tyrosine kinase FLT3, the cytoplasmic signal transduction molecules (KLF10/TIEG1 and NUMB), an antiapoptotic protein (BAG1), a microtubule motor protein (KIF22), a protein involved in synaptic vesicle function in neurons (SYP), a structural protein (CTNNB1) and SNCAIP. Confers constitutive instability to HIPK2 through proteasomal degradation. It is thereby involved in many cellular processes such as apoptosis, tumor suppression, cell cycle, axon guidance, transcription regulation, spermatogenesis and TNF-alpha signaling. Has some overlapping function with SIAH2. Induces apoptosis in cooperation with PEG3. Upon nitric oxid (NO) generation that follows apoptotic stimulation, interacts with S-nitrosylated GAPDH, mediating the translocation of GAPDH to the nucleus. GAPDH acts as a stabilizer of SIAH1, facilitating the degradation of nuclear proteins.

Artikel nummer : BOSSBS-3596R-CY7

UOM: 1 * 100 µl

Leverantör: Bioss

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Beskrivning: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates E3 ubiquitin ligase activity either through direct binding to substrates or by functioning as the essential RING domain subunit of larger E3 complexes. Triggers the ubiquitin-mediated degradation of many substrates, including proteins involved in transcription regulation (ELL2, MYB, POU2AF1, PML and RBBP8), a cell surface receptor (DCC), the cell-surface receptor-type tyrosine kinase FLT3, the cytoplasmic signal transduction molecules (KLF10/TIEG1 and NUMB), an antiapoptotic protein (BAG1), a microtubule motor protein (KIF22), a protein involved in synaptic vesicle function in neurons (SYP), a structural protein (CTNNB1) and SNCAIP. Confers constitutive instability to HIPK2 through proteasomal degradation. It is thereby involved in many cellular processes such as apoptosis, tumor suppression, cell cycle, axon guidance, transcription regulation, spermatogenesis and TNF-alpha signaling. Has some overlapping function with SIAH2. Induces apoptosis in cooperation with PEG3. Upon nitric oxid (NO) generation that follows apoptotic stimulation, interacts with S-nitrosylated GAPDH, mediating the translocation of GAPDH to the nucleus. GAPDH acts as a stabilizer of SIAH1, facilitating the degradation of nuclear proteins.

Artikel nummer : BOSSBS-3596R-FITC

UOM: 1 * 100 µl

Leverantör: Bioss

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Beskrivning: Anti-PEG3 Mouse Monoclonal Antibody [clone: OTI1B2]

Artikel nummer : ORIGTA801958

UOM: 1 * 100 µl

Leverantör: OriGene

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Beskrivning: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates E3 ubiquitin ligase activity either through direct binding to substrates or by functioning as the essential RING domain subunit of larger E3 complexes. Triggers the ubiquitin-mediated degradation of many substrates, including proteins involved in transcription regulation (ELL2, MYB, POU2AF1, PML and RBBP8), a cell surface receptor (DCC), the cell-surface receptor-type tyrosine kinase FLT3, the cytoplasmic signal transduction molecules (KLF10/TIEG1 and NUMB), an antiapoptotic protein (BAG1), a microtubule motor protein (KIF22), a protein involved in synaptic vesicle function in neurons (SYP), a structural protein (CTNNB1) and SNCAIP. Confers constitutive instability to HIPK2 through proteasomal degradation. It is thereby involved in many cellular processes such as apoptosis, tumor suppression, cell cycle, axon guidance, transcription regulation, spermatogenesis and TNF-alpha signaling. Has some overlapping function with SIAH2. Induces apoptosis in cooperation with PEG3. Upon nitric oxid (NO) generation that follows apoptotic stimulation, interacts with S-nitrosylated GAPDH, mediating the translocation of GAPDH to the nucleus. GAPDH acts as a stabiliser of SIAH1, facilitating the degradation of nuclear proteins.

Artikel nummer : BOSSBS-3596R-A750

UOM: 1 * 100 µl

Leverantör: Bioss

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Beskrivning: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates E3 ubiquitin ligase activity either through direct binding to substrates or by functioning as the essential RING domain subunit of larger E3 complexes. Triggers the ubiquitin-mediated degradation of many substrates, including proteins involved in transcription regulation (ELL2, MYB, POU2AF1, PML and RBBP8), a cell surface receptor (DCC), the cell-surface receptor-type tyrosine kinase FLT3, the cytoplasmic signal transduction molecules (KLF10/TIEG1 and NUMB), an antiapoptotic protein (BAG1), a microtubule motor protein (KIF22), a protein involved in synaptic vesicle function in neurons (SYP), a structural protein (CTNNB1) and SNCAIP. Confers constitutive instability to HIPK2 through proteasomal degradation. It is thereby involved in many cellular processes such as apoptosis, tumor suppression, cell cycle, axon guidance, transcription regulation, spermatogenesis and TNF-alpha signaling. Has some overlapping function with SIAH2. Induces apoptosis in cooperation with PEG3. Upon nitric oxid (NO) generation that follows apoptotic stimulation, interacts with S-nitrosylated GAPDH, mediating the translocation of GAPDH to the nucleus. GAPDH acts as a stabilizer of SIAH1, facilitating the degradation of nuclear proteins.

Artikel nummer : BOSSBS-3596R-A647

UOM: 1 * 100 µl

Leverantör: Bioss

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Beskrivning: Anti-PEG3 Rabbit Polyclonal Antibody (Cy5.5®)

Artikel nummer : BIRBORB123335-100

UOM: 1 * 100 µl

Leverantör: Biorbyt

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Beskrivning: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates E3 ubiquitin ligase activity either through direct binding to substrates or by functioning as the essential RING domain subunit of larger E3 complexes. Triggers the ubiquitin-mediated degradation of many substrates, including proteins involved in transcription regulation (ELL2, MYB, POU2AF1, PML and RBBP8), a cell surface receptor (DCC), the cell-surface receptor-type tyrosine kinase FLT3, the cytoplasmic signal transduction molecules (KLF10/TIEG1 and NUMB), an antiapoptotic protein (BAG1), a microtubule motor protein (KIF22), a protein involved in synaptic vesicle function in neurons (SYP), a structural protein (CTNNB1) and SNCAIP. Confers constitutive instability to HIPK2 through proteasomal degradation. It is thereby involved in many cellular processes such as apoptosis, tumor suppression, cell cycle, axon guidance, transcription regulation, spermatogenesis and TNF-alpha signaling. Has some overlapping function with SIAH2. Induces apoptosis in cooperation with PEG3. Upon nitric oxid (NO) generation that follows apoptotic stimulation, interacts with S-nitrosylated GAPDH, mediating the translocation of GAPDH to the nucleus. GAPDH acts as a stabiliser of SIAH1, facilitating the degradation of nuclear proteins.

Artikel nummer : BOSSBS-3596R-A680

UOM: 1 * 100 µl

Leverantör: Bioss

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Beskrivning: Anti-PEG3 Mouse Monoclonal Antibody [clone: 1F12]

Artikel nummer : ORIGCF801961

UOM: 1 * 100 µG

Leverantör: OriGene

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Beskrivning: Anti-PEG3 Mouse Monoclonal Antibody [clone: OTI1F12]

Artikel nummer : ORIGTA801961

UOM: 1 * 100 µl

Leverantör: OriGene

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Beskrivning: Anti-PEG3 Rabbit Polyclonal Antibody (PE (Phycoerythrin)/Cy7®)

Artikel nummer : BIRBORB131074-100

UOM: 1 * 100 µl

Leverantör: Biorbyt

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Beskrivning: Anti-PEG3 Rabbit Polyclonal Antibody

Artikel nummer : ANTIA92099-100

UOM: 1 * 100 µl

Leverantör: ANTIBODIES.COM

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Beskrivning: A water soluble azide functionalized- TAMRA dye. The water-soluble PEG spacer minimizes the interaction between the dye and the biomolecule to be labeled.

Artikel nummer : J64510.MB

UOM: 1 * 25 mg

Leverantör: Thermo Fisher Scientific

Säkerhetsdatablad Certifikat Sale

Beskrivning: A green fluorescent rhodamine dye for click chemistry reactions and fluorescence microscopy. The PEG spacer improves water solubility and also reduces any steric effect of the dye on the molecule to be labeled.

Artikel nummer : J65107.MB

UOM: 1 * 25 mg

Leverantör: Thermo Fisher Scientific

Säkerhetsdatablad Certifikat Sale

Beskrivning: Anti-PEG3 Rabbit Polyclonal Antibody (Cy3®)

Artikel nummer : BIRBORB114802-100

UOM: 1 * 100 µl

Leverantör: Biorbyt

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Beskrivning: Anti-PEG3 Rabbit Polyclonal Antibody (FITC (Fluorescein))

Artikel nummer : BIRBORB14201-100

UOM: 1 * 100 µG

Leverantör: Biorbyt

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Beskrivning: Anti-PEG3 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))

Artikel nummer : BIRBORB113817-100

UOM: 1 * 100 µl

Leverantör: Biorbyt

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