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Image Unavailable-BOSSBS-2428R-CY3

Anti-IL9 Rabbit Polyclonal Antibody (Cy3®)

Artikel nummer : (BOSSBS-2428R-CY3)
Leverantör: Bioss
Beskrivning: The protein encoded by this gene is a cytokine that actsas a regulator of a variety of hematopoietic cells. This cytokinestimulates cell proliferation and prevents apoptosis. It functionsthrough the interleukin 9 receptor (IL9R), which activatesdifferent signal transducer and activator (STAT) proteins and thusconnects this cytokine to various biological processes. The geneencoding this cytokine has been identified as a candidate gene forasthma. Genetic studies on a mouse model of asthma demonstratedthat this cytokine is a determining factor in the pathogenesis ofbronchial hyperresponsiveness. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl
Product Image-GT20-50

J.T.Baker® Endonuclease

Leverantör: Avantor
Beskrivning: J.T.Baker® Endonuclease Biotech Reagent meets the strictest cGMP standards and is designed for the degradation of both single stranded and double stranded DNA and RNA. J.T.Baker® Endonuclease Biotech Reagent is used to ensure host cell DNA impurities are removed; driving process efficiency by lowering viscosity and preventing aggregation. J.T.Baker® Endonuclease Biotech Reagent is an enzyme based upon the native endonuclease of Serratia marcescens, enabling rapid clearance of residual DNA and RNA during the production and purification of both recombinant proteins and viral vectors. Non-animal origin. Absence of proteolytic activity. The purity of materials in non-negotiable. J.T.Baker® Endonuclease Biotech Reagent acts to degrade and eliminate extraneous genetic material, ensuring the pristine quality of your final product.

Säkerhetsdatablad Certifikat

Product Image-BE-401

Proteiners fysikaliska egenskaper

Artikel nummer : (BE-401)
Leverantör: G-Biosciences
Beskrivning: Laborationen fysikaliska egenskaperna hos proteiner är en laboration för att undersöka de fysikaliska egenskaperna hos olika proteiner. Eleverna kommer att lära sig om proteinlöslighet och hur lösligheten påverkas av temperatur, pH, salt och dielektrisk konstant. Laborationen ger kunskap om proteinutfällning, denaturering på grund av pH förändring, hög salthalt, organiska lösningsmedel och proteindenaturering som ett resultat av hög temperatur. Dessutom kommer satsen att demonstrera hur ämnen som inte är proteiner, såsom detergenter, drastiskt förändrar proteinmolekylers fysikaliska egenskaper och som ett resultat, att förstå betydelsen av detergenter inom proteinsolubilisering. Denna laboration innehåller analys av tre olika sorters rena proteiner. Efter tillsats av detergent undersöks på nytt proteinernas fysikaliska egenskaper. Eleverna utmanas att tänka över hur fysikaliska egenskaper hos proteinmolekyler kan användas för rening och karaktärisering av proteiner och tillämpar därefter sina slutsatser på ett försöksprov med ett komplext vävnadsextrakt.
UOM: 1 * 1 KIT
Image Unavailable-BOSSBS-13204R-FITC

Anti-FOXL2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Artikel nummer : (BOSSBS-13204R-FITC)
Leverantör: Bioss
Beskrivning: Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis throught transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Is a regulator of CYP19 expression (By similarity). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity). Is a transcriptional repressor of STAR. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-15406R-A350

Anti-Hamartin Rabbit Polyclonal Antibody (ALEXA FLUOR® 350)

Artikel nummer : (BOSSBS-15406R-A350)
Leverantör: Bioss
Beskrivning: Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder characterised by mental retardation and the widespread development of distinctive tumors termed hamartomas. Two different genetic loci have been linked to TSC; one of these loci, the tuberous sclerosis-2 gene (TSC2), encodes a protein called tuberin and the other loci, tuberous sclerosis-1 gene (TSC1), encodes a protein called hamartin. Tuberin and hamartin interact with each other forming a cystoplasmic complex. Hamartin interacts with the ezrin-radixin-moesin (ERM) family of actin-binding proteins and inhibition of hamartin activity results in loss of cell adhesion. Hamartin is present in most adult tissues with strong expression in brain, heart, and kidney.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11248R-FITC

Anti-ARHGAP26 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Artikel nummer : (BOSSBS-11248R-FITC)
Leverantör: Bioss
Beskrivning: Cellular signaling by G-proteins is down-regulated by GTPase-activating proteins (GAPs), which increase the rate of GTP hydroylsis. The GTPase regulator associated with focal adhesion kinase (GRAF) has GAP activity toward Rho A and Cdc42, but not Rac1. GRAF is ubiquitously expressed with high levels in heart and brain. Expression of GRAF causes clearing of stress fibers and formation of long actin based filopodial-like extensions. Fusion of MLL with GRAF, MLL/GRAF, is included in a rare genetic subgroup of acute myeloid leukemia (AML) cases.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11248R-A488

Anti-ARHGAP26 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Artikel nummer : (BOSSBS-11248R-A488)
Leverantör: Bioss
Beskrivning: Cellular signaling by G-proteins is down-regulated by GTPase-activating proteins (GAPs), which increase the rate of GTP hydroylsis. The GTPase regulator associated with focal adhesion kinase (GRAF) has GAP activity toward Rho A and Cdc42, but not Rac1. GRAF is ubiquitously expressed with high levels in heart and brain. Expression of GRAF causes clearing of stress fibers and formation of long actin based filopodial-like extensions. Fusion of MLL with GRAF, MLL/GRAF, is included in a rare genetic subgroup of acute myeloid leukemia (AML) cases.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11248R-HRP

Anti-ARHGAP26 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Artikel nummer : (BOSSBS-11248R-HRP)
Leverantör: Bioss
Beskrivning: Cellular signaling by G-proteins is down-regulated by GTPase-activating proteins (GAPs), which increase the rate of GTP hydroylsis. The GTPase regulator associated with focal adhesion kinase (GRAF) has GAP activity toward Rho A and Cdc42, but not Rac1. GRAF is ubiquitously expressed with high levels in heart and brain. Expression of GRAF causes clearing of stress fibers and formation of long actin based filopodial-like extensions. Fusion of MLL with GRAF, MLL/GRAF, is included in a rare genetic subgroup of acute myeloid leukemia (AML) cases.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11448R-A350

Anti-AANAT Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Artikel nummer : (BOSSBS-11448R-A350)
Leverantör: Bioss
Beskrivning: Arylalkylamine N-acetyltransferase belongs to the superfamily of acetyltransferases. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for seasonal reproduction, modulates the function of the circadian clock in the suprachiasmatic nucleus, and influences activity and sleep. This enzyme is rapidly inactivated when animals are exposed to light at night. This protein is 80% identical to sheep and rat AA-NAT. Arylalkylamine N-acetyltransferase may contribute a multifactorial genetic diseases such as altered behavior in sleep/wake cycle.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11455R-FITC

Anti-DCAMKL1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Artikel nummer : (BOSSBS-11455R-FITC)
Leverantör: Bioss
Beskrivning: Lissencephaly (smooth brain) is an abnormality of brain development characterized by incomplete neuronal migration and a smooth cerebral surface, manifesting as severe mental retardation. Genetic analysis has identified two proteins that are mutated in some cases of lissencephaly, designated lissencephaly-1 protein (LIS1) and doublecortin. LIS1 displays sequence homology to ?subunits of heterotrimeric G proteins, and doublecortin contains a consensus Abl phosphorylation site. In addition, the DCAMKL1 (doublecortin-like and CAM kinase-like 1) protein shows homology to doublecortin. All three proteins are highly expressed in developing brain and may function together to regulate microtubules involved in neuronal migration. The DCAMKL1 protein encodes a functional kinase that is capable of phosphorylating myelin basic protein and itself, but its kinase activity does not appear to affect its microtubule polymerization activity.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11337R-CY7

Anti-C1QC/C1QG Rabbit Polyclonal Antibody (Cy7®)

Artikel nummer : (BOSSBS-11337R-CY7)
Leverantör: Bioss
Beskrivning: C1q, a subcomponent of the classical complement pathway, is composed of nine subunits that mediate classical complement activation and thereby play an important role in the immune response. Six of these subunits are disulfide-linked dimers of chains A and B, while three of these subunits, designated C1q-A through C1q-C, are disulfide-linked dimers of chain C. The presence of receptors for C1q on effector cells modulates its activity, which may be antibody-dependent or independent. Macrophages are the primary source of C1q, while anti-inflammatory drugs as well as cytokines differentially regulate expression of the mRNA, as well as the protein. However, its ability to modulate the interaction of platelets with collagen and immune complexes suggests C1q influences homeostasis as well as other immune activities, and perhaps thrombotic complications resulting from immune injury. Defects in C1q-A, C1q-B and C1q-C cause inactivation of the classical pathway, leading to a rare genetic disorder characterized by lupus-like symptoms.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11337R-A350

Anti-C1QC/C1QG Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Artikel nummer : (BOSSBS-11337R-A350)
Leverantör: Bioss
Beskrivning: C1q, a subcomponent of the classical complement pathway, is composed of nine subunits that mediate classical complement activation and thereby play an important role in the immune response. Six of these subunits are disulfide-linked dimers of chains A and B, while three of these subunits, designated C1q-A through C1q-C, are disulfide-linked dimers of chain C. The presence of receptors for C1q on effector cells modulates its activity, which may be antibody-dependent or independent. Macrophages are the primary source of C1q, while anti-inflammatory drugs as well as cytokines differentially regulate expression of the mRNA, as well as the protein. However, its ability to modulate the interaction of platelets with collagen and immune complexes suggests C1q influences homeostasis as well as other immune activities, and perhaps thrombotic complications resulting from immune injury. Defects in C1q-A, C1q-B and C1q-C cause inactivation of the classical pathway, leading to a rare genetic disorder characterized by lupus-like symptoms.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11648R-A488

Anti-TMEM59L Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Artikel nummer : (BOSSBS-11648R-A488)
Leverantör: Bioss
Beskrivning: BSMAP is a 342 amino acid type-I membrane glycoprotein that localizes to organelle membranes and belongs to the TMEM59 family. Expressed at high levels in brain tissue, BSMAP is thought to play a role in brain function and central nervous system activity. The gene encoding BSMAP maps to human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11648R-CY5

Anti-TMEM59L Rabbit Polyclonal Antibody (Cy5®)

Artikel nummer : (BOSSBS-11648R-CY5)
Leverantör: Bioss
Beskrivning: BSMAP is a 342 amino acid type-I membrane glycoprotein that localizes to organelle membranes and belongs to the TMEM59 family. Expressed at high levels in brain tissue, BSMAP is thought to play a role in brain function and central nervous system activity. The gene encoding BSMAP maps to human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11648R-A680

Anti-TMEM59L/BSMAP Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel nummer : (BOSSBS-11648R-A680)
Leverantör: Bioss
Beskrivning: BSMAP is a 342 amino acid type-I membrane glycoprotein that localizes to organelle membranes and belongs to the TMEM59 family. Expressed at high levels in brain tissue, BSMAP is thought to play a role in brain function and central nervous system activity. The gene encoding BSMAP maps to human chromosome 19, which consists of over 63 million bases, houses approximately 1400 genes and is recognised for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0299R-FITC

Anti-AK1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Artikel nummer : (BOSSBS-0299R-FITC)
Leverantör: Bioss
Beskrivning: Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl
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Lager för denna produkt är begränsat, men kan vara tillgänglig i ett lager nära dig. Se till att du är inloggad på hemsidan så att tillgängligt lager kan visas. Om call fortfarande visas och du behöver hjälp, ring oss på 08-621 34 20.
Lager för denna produkt är begränsat, men kan vara tillgänglig i ett lager nära dig. Se till att du är inloggad på hemsidan så att tillgängligt lager kan visas. Om call fortfarande visas och du behöver hjälp, ring oss på 08-621 34 20.
VWR International AB säljer bara etanol till skattebefriade kunder. Denna produkt ä reglerad enligt svensk lagstiftning. Om ytterligare information krävs av dig kommer du att kontaktas via e-post.
VWR International AB säljer bara etanol till skattebefriade kunder.
Denna produkt ä reglerad enligt svensk lagstiftning. Om ytterligare information krävs av dig kommer du att kontaktas via email.
Produkten har blockerats av din organisation. Vänligen kontakta din inköpsavdelning för mer information.
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Denna produkt är inte längre tillgänglig. Alternativ kan vara tillgängliga genom att söka med VWR art.nr ovan. Om du behöver ytterligare hjälp, ring VWR Kundservice på 08-621 34 20.
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