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Image Unavailable-BOSSBS-12432R-CY3

Anti-DOCK4 Rabbit Polyclonal Antibody (Cy3®)

Artikel nummer : (BOSSBS-12432R-CY3)
Leverantör: Bioss
Beskrivning: DOCK 4 is a cytoplasmic peripheral membrane protein that belongs to the DOCK family of cytokinesis-regulating proteins. Expressed ubiquitously with highest expression in prostate, ovary and skeletal muscle, DOCK 4 functions as a guanine nucleotide exchange factor (GEF) that activates the small GTPase Rap 1 and, via this activation, plays a role in the regulation of adherens junctions between cells. Similar to other DOCK family members, DOCK 4 contains an N-terminal SH3 domain, a C-terminal proline-rich region and two internal DOCK homology regions designated DHR1 and DHR2. Defects in the gene encoding DOCK 4 result in the inactivation of Rap 1 and are, thus, implicated in the pathogenesis of various cancers such as ovarian, prostate, glioma and colorectal carcinomas. Four isoforms of DOCK 4 are expressed due to alternative splicing events.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12432R-A647

Anti-DOCK4 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Artikel nummer : (BOSSBS-12432R-A647)
Leverantör: Bioss
Beskrivning: DOCK 4 is a cytoplasmic peripheral membrane protein that belongs to the DOCK family of cytokinesis-regulating proteins. Expressed ubiquitously with highest expression in prostate, ovary and skeletal muscle, DOCK 4 functions as a guanine nucleotide exchange factor (GEF) that activates the small GTPase Rap 1 and, via this activation, plays a role in the regulation of adherens junctions between cells. Similar to other DOCK family members, DOCK 4 contains an N-terminal SH3 domain, a C-terminal proline-rich region and two internal DOCK homology regions designated DHR1 and DHR2. Defects in the gene encoding DOCK 4 result in the inactivation of Rap 1 and are, thus, implicated in the pathogenesis of various cancers such as ovarian, prostate, glioma and colorectal carcinomas. Four isoforms of DOCK 4 are expressed due to alternative splicing events.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4258R-A680

Anti-Vesicle docking protein p115 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel nummer : (BOSSBS-4258R-A680)
Leverantör: Bioss
Beskrivning: General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity (By similarity).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5289R-FITC

Anti-DOK1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Artikel nummer : (BOSSBS-5289R-FITC)
Leverantör: Bioss
Beskrivning: Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13027R-HRP

Anti-DOK1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Artikel nummer : (BOSSBS-13027R-HRP)
Leverantör: Bioss
Beskrivning: Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5290R-A350

Anti-DOK1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Artikel nummer : (BOSSBS-5290R-A350)
Leverantör: Bioss
Beskrivning: Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5289R-A350

Anti-DOK1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Artikel nummer : (BOSSBS-5289R-A350)
Leverantör: Bioss
Beskrivning: Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5289R-CY5

Anti-DOK1 Rabbit Polyclonal Antibody (Cy5®)

Artikel nummer : (BOSSBS-5289R-CY5)
Leverantör: Bioss
Beskrivning: Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13027R-A647

Anti-DOK1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Artikel nummer : (BOSSBS-13027R-A647)
Leverantör: Bioss
Beskrivning: Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5289R-A680

Anti-DOK1 Tyr362 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel nummer : (BOSSBS-5289R-A680)
Leverantör: Bioss
Beskrivning: Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukaemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13027R-A680

Anti-DOK1 Ser450 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel nummer : (BOSSBS-13027R-A680)
Leverantör: Bioss
Beskrivning: Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13118R-CY5

Anti-EXOC2 Rabbit Polyclonal Antibody (Cy5®)

Artikel nummer : (BOSSBS-13118R-CY5)
Leverantör: Bioss
Beskrivning: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12433R

Anti-DOCK5 Rabbit Polyclonal Antibody

Artikel nummer : (BOSSBS-12433R)
Leverantör: Bioss
Beskrivning: DOCK 5 is a 1,870 amino acid protein belonging to the DOCK family of cytokinesis-regulating proteins. This cytoplasmic peripheral membrane protein activates Rac 1 and Rac 2 small GTPases, while presumably acting as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. DOCK 5 contains one DHR-1 (CZH-1) domain, one DHR-2 (CZH-2) domain and one SH3 domain. The DHR-2 domain is a putative GEF activity mediator. In mice, spontaneous mutation of the gene encoding DOCK 5 leads to deletion of the DHR-1 domain, which functions to bind phospholipids and assists in protein-protein interactions, resulting in rupture of lens cataract (RLC). Due to siRNA knockdown studies, it is suspected that DOCK 5 may also be an important mediator of CrkII/CrkL regulation of Caco-2 migration and spreading on COL4. There are two isoforms of DOCK 5 that exist as a result of alternative splicing events.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13118R-CY7

Anti-EXOC2 Rabbit Polyclonal Antibody (Cy7®)

Artikel nummer : (BOSSBS-13118R-CY7)
Leverantör: Bioss
Beskrivning: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12432R-CY7

Anti-DOCK4 Rabbit Polyclonal Antibody (Cy7®)

Artikel nummer : (BOSSBS-12432R-CY7)
Leverantör: Bioss
Beskrivning: DOCK 4 is a cytoplasmic peripheral membrane protein that belongs to the DOCK family of cytokinesis-regulating proteins. Expressed ubiquitously with highest expression in prostate, ovary and skeletal muscle, DOCK 4 functions as a guanine nucleotide exchange factor (GEF) that activates the small GTPase Rap 1 and, via this activation, plays a role in the regulation of adherens junctions between cells. Similar to other DOCK family members, DOCK 4 contains an N-terminal SH3 domain, a C-terminal proline-rich region and two internal DOCK homology regions designated DHR1 and DHR2. Defects in the gene encoding DOCK 4 result in the inactivation of Rap 1 and are, thus, implicated in the pathogenesis of various cancers such as ovarian, prostate, glioma and colorectal carcinomas. Four isoforms of DOCK 4 are expressed due to alternative splicing events.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6234R-CY5

Anti-DOK3 Rabbit Polyclonal Antibody (Cy5®)

Artikel nummer : (BOSSBS-6234R-CY5)
Leverantör: Bioss
Beskrivning: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate Abl functionDOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate Abl function. There are 4 isoforms generated by alternative splicing.
UOM: 1 * 100 µl
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Lager för denna produkt är begränsat, men kan vara tillgänglig i ett lager nära dig. Se till att du är inloggad på hemsidan så att tillgängligt lager kan visas. Om call fortfarande visas och du behöver hjälp, ring oss på 08-621 34 20.
VWR International AB säljer bara etanol till skattebefriade kunder. Denna produkt ä reglerad enligt svensk lagstiftning. Om ytterligare information krävs av dig kommer du att kontaktas via e-post.
VWR International AB säljer bara etanol till skattebefriade kunder.
Denna produkt ä reglerad enligt svensk lagstiftning. Om ytterligare information krävs av dig kommer du att kontaktas via email.
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