Adenosine free base ≥98%, white powder
Leverantör: MP Biomedicals
Synonyms:
9-β-D-Ribofuranosyladenine, (2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol, Adenine-9-β-D-ribofuranoside, Adenine riboside
Adenosine is a nucleotide resulting from the union of one molecule of sugar -- d-ribose -- with a base -- l-adenine.
Adenosine is active in cardiovascular disorders. It is indicated in cases of angina pectoris on account of its property of increasing the coronary output and in cases of hypertension on account of its vasodilator action. It is also active on the peripheral circulation, dilating the capillary vessels. It has also been recommended in the treatment of agranulocytosis. It induces apoptosis in human leukemia HL-60 cells and also has anti-arrhythmic properties.
Endogenous neurotransmitter at adenosine receptors. Cardioprotective effects may relate to activation of A1 adenosine receptors. The antiplatelet and anti -inflammatory actions of adenosine appear to be mediated via the A2 adenosine receptor. In contrast, adenosine appears to be a pro-inflammatory mediator in asthma and chronic obstructive pulmonary disease (COPD).
Fairly soluble in cold water, soluble in room temperature water, freely soluble in hot water; soluble in 1 N hydrochloric acid (50 mg/ml - clear and colourless); insoluble in alcohol.
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Formel:
C₁₀H₁₃N₅O₄ MW: 267,24 g/mol Storage Temperature: Frys |
MDL Number:
MFCD00005752 CAS nummer: 58-61-7 EINECS: 200-389-9 |
Specifikation testresultat
| Identity Test | Passes |
| Purity | ≥98% |
| FTIR | Conforms to Standard |
| Melting Point | 228 - 236 °C |
| UV/VIS: l max (1N HCl) | 255 - 260 nm |
| OD250/OD260 | 0,80 - 0,90 |
| OD280/OD260 | 0,17 - 0,24 |
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