Cocarboxylase tetrahydrate, EMPROVE® API, SAFC®

Leverantör: MERCK PRODUCTION CHEMICALS

Synonyms: 2-(3-((4-Amino-2-methylpyrimidin-5-yl)methyl)-4-methylthiazol-3-ium-5-yl)ethyl dihydrogen diphosphate tetrahydrate, Thiamine diphosphoric acid ester tetrahydrate

5.00111.5000 5.00111.0100
5.00111.5000EA 0 SEK
5.00111.5000 5.00111.0100
Cocarboxylase tetrahydrate, EMPROVE® API, SAFC®
Cocarboxylase tetrahydrate
Formel: C₁₂H₁₈N₄O₇P₂S·4H₂O
MW: 496,37 g/mol
Storage Temperature: Omgivande
MDL Number: MFCD00150680
CAS nummer: 68684-55-9
EINECS: 205-230-7

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Specifikation testresultat

Assay (HPLC, calc.on anhydrous substance) 96.0 - 101.0 %
Identity (IR-spectrum) passes test
pH-value (10 %; water) 2.4 - 3.2
Chloride (Cl) (Ion Chromatography) ≤ 0.025 %
Free phosphate (PO₄) ≤ 1.0 %
Al (Aluminium) (#) ≤ 0.0010 %
As (Arsenic) ≤ 0.0003 %
Ni (Nickel) (#) ≤ 0.0002 %
Thiamine phosphoric acid ester (HPLC) ≤ 1.5 %
Thiamin (HPLC) ≤ 0.1 %
Dithiamintriphosphate (HPLC) ≤ 0.25 %
Impurity A (HPLC) ≤ 0.1
Impurity B (HPLC) ≤ 0.1
Related substances (HPLC) ≤ 1.5 %
Water 14.0 - 16.5 %
Endotoxins < 12
Residual Solvents of class 3 ((2-Propanol) according to ICH Q3C) ≤ 0.2 %
Other residual solvents (according to ICH Q3C) excluded by manufacturing process
Microbiological test passes test
Colony count (aerobic bacteria (TAMC)) ≤ 1000 CFU/g
Colony count (Yeasts and moulds (TYMC)) ≤ 100 CFU/g
E.coli passes test

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