PI103 ≥97%
Leverantör: ENZO LIFE SCIENCES AG
Synonyms:
PI-103, 3-(4-Morpholinopyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl)phenol
Potent, cell permeable and ATP-competitive inhibitor of DNA-PK, phosphoinositide 3-kinase (PI(3)K), the rapamycin-sensitive (mTORC1) and rapamycin-insensitive (mTORC2) complexes of the protein kinase mTOR. Exhibits little activity towards a panel of more than 40 other kinases even at concentrations as high as 10µM. Effectively blocks cell proliferation in glioma cell lines both in vitro and in vivo.
- Inhibitor of DNA-PK, PI3 kinase and mTOR
Off-white solid.
Soluble in DMSO (5mg/ml; warm).
Formel:
C₁₉H₁₆N₄O₃ MW: 348,36 g/mol Storage Temperature: Frys |
MDL Number:
MFCD11983145 CAS nummer: 371935-74-9 |
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