Toluen-α-sulfonylfluorid ≥99% (by GC-FID)
Leverantör: ENZO LIFE SCIENCES AG
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Fara
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Synonyms:
PMSF, Phenylmethanesulphonyl fluoride, Phenylmethylsulphonyl fluoride, α-Toluenesulphonyl fluoride
Irreversible inhibitor of serine proteases. Widely used fatty acid amid hydrolase (FAAH) inhibitor for pretreatment of brain membrane preparations when testing CB1 receptor activity. Spleen membranes used for CB2 studies do not require this pretreatment, as FAAH activity is absent in these cells. Inhibits also cysteine proteases like papain (reversible by DTT treatment, as well as internucleosomal DNA fragmentation in immature thymocytes. For a related, more stable inhibitor see AEBSF.
- Inhibitor of serine proteases and FAAH
White to off-white needle crystals.
Soluble in 100% ethanol, methanol or isopropanol; insoluble in water.
Formel:
C₇H₇FO₂S MW: 174,2 g/mol Kokpunkt: 80…85 °C (0,3 mmHg) Smältpunkt: 91…92 °C Storage Temperature: Omgivande |
MDL Number:
MFCD00007424 CAS nummer: 329-98-6 EINECS: 206-350-2 UN: 2923 ADR: 8,III |
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