MK-886 ≥98%

Leverantör: ENZO LIFE SCIENCES AG

Synonyms: 3-(3-(tert-Butylthio)-1-(4-chlorobenzyl)-5-isopropyl-1H-indol-2-yl)-2,2-dimethylpropanoic acid, L-663,536, 3-[1-(p-Chlorobenzyl)-5-(isopropyl)-3-t-butylthioindol-2-yl]-2,2-dimethylpropanoic acid Na

BMLEI2660005 BMLEI2660025
ENZOBMLEI2660005EA 1225 SEK
ENZOBMLEI2660005 ENZOBMLEI2660025
MK-886 ≥98%
MK-886

Inhibitor of PPARα activation. Inhibits 5-lipoxygenase-activating protein (FLAP) and leukotriene biosynthesis. Binds to FLAP with high affinity and prevents the activation of 5-lipoxygenase. IC50’s for leukotriene biosynthesis: 2.5 nM in intact leukocytes; 1.1 µM in whole blood. Induces apoptosis through the mitochondrial pathway.


  • FLAP inhibitor


White solid.


Soluble in 100% ethanol (25mg/ml) or DMSO (25mg/ml).

Formel: C₂₇H₃₃ClNO₂S·Na
MW: 494,0 g/mol
Storage Temperature: Omgivande
MDL Number: MFCD00876710
CAS nummer: 118414-82-7
https://digitalassets.avantorsciences.com/adaptivemedia/rendition?id=91a1291a05c96db156c21a172c0e177f09b0113f&vid=1bd1cbdece43c0726fdd53ac4546356678ec2c7b&prid=web&clid=SAPDAM

Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Läs mer About VWR