3-Morpholinosydnonimine 98 HPLC_ANALYSMETOD

Leverantör: ENZO LIFE SCIENCES

Synonyms: Linsidomine, SIN-1

BMLCN2450020 BMLCN2450100
ENZOBMLCN2450020EA 965 SEK
ENZOBMLCN2450020 ENZOBMLCN2450100
3-Morpholinosydnonimine 98 HPLC_ANALYSMETOD
3-Morpholinosydnonimine

SIN-1 is a metabolite of molsidomine which decomposes spontaneously in solution in the presence of oxygen, releasing NO and superoxide anion under physiological conditions. Since NO and superoxide react to form peroxynitrite, SIN-1 may actually produce peroxynitrite under physiological conditions. It is a potent vasodilator and inhibitor of platelet aggregation and produces significant protective effects in myocardial ischemia-reperfusion. The effects of SIN-1 are markedly attenuated by nitroglycerin-induced tolerance. Inhibits cysteine proteases.


  • Releases NO and superoxide anion under physiological conditions


White to off-white solid.


Soluble in water (25mg/ml), 100% ethanol or DMSO (>5mg/ml).

Formel: C₆H₁₀N₄O₂·HCl
MW: 206.6 g/mol
Smältpunkt: 186…187 °C
Storage Temperature: Frys
CAS nummer: 33876-97-0
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