H-89 dihydrochloride ≥99%

Leverantör: ENZO LIFE SCIENCES AG

BMLEI1960005 BMLEI1960025
ENZOBMLEI1960005EA 1475 SEK
ENZOBMLEI1960005 ENZOBMLEI1960025
H-89 dihydrochloride ≥99%
H-89 dihydrochloride

Protein kinase inhibitor


Cell permeable potent and selective inhibitor of cAMP- and cGMP-dependent protein kinases (PKA, Ki=48nM, and PKG) and protein kinase Cµ (PKCµ). In contrast, most other protein kinase C (PKC) isotypes are much more weakly inhibited. Also inhibits Ca2+/calmodulin-dependent protein kinase II, casein kinase I and myosin light chain kinase. Induces apoptosis. Concentration range for cultured cells 30-100μM: osteoblastic cells, renal proximal tubule cells and Xenopus oocytes. 

Formel: C₂₀H₂₀BrN₃O₂S·2HCl
CAS nummer: 127243-85-0
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