Paclitaxel 98
Leverantör: ENZO LIFE SCIENCES
Ultra-pure; stabilizes microtubules
Antitumor agent. Stabilizes microtubules and lowers the critical concentration for tubulin polymerization. Reversibly binds to polymerized tubulin. Inhibits protein isoprenylation and induces apoptosis in PC-3 human prostate cancer cells. The checkpoint of mitotic spindle assembly, aberrant activation of cyclin-dependent kinases (CKDs) and the c-Jun N-terminal kinase/stress activated protein kinase (JNK/SAPK) are involved in Paclitaxel-induced apoptosis.
Isolated from the bark of the Pacific Yew tree (Taxus brevifolia)
Formel:
C₄₇H₅₁NO₁₄ MW: 853.91 g/mol |
MDL Number:
MFCD00869953 CAS nummer: 33069-62-4 |
|
Learn more

About VWR
Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...