N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine

Leverantör: Apollo Scientific

Synonyms: Gefitinib

BISN0101-1G BISN0101-5G
APOSBISN0101-1GEA 1625 SEK
APOSBISN0101-1G APOSBISN0101-5G
N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine

Gefitinibis an EGFR inhibitor for Tyr1173, Tyr992, Tyr1173 and Tyr992 in the NR6wtEGFR and NR6W cells with IC50 of 37 nM, 37nM, 26 nM and 57 nM, respectively, and interrupts signaling through the epidermal growth factor receptor (EGFR) in target cells.

Formel: C₂₂H₂₄ClFN₄O₃
MW: 446,91 g/mol
Smältpunkt: 196 °C
Storage Temperature: Kylskåp
MDL Number: MFCD04307832
CAS nummer: 184475-35-2

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