N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
Leverantör: Apollo Scientific
Synonyms:
Gefitinib
BISN0101-1G
BISN0101-5G
APOSBISN0101-1GEA
1625
SEK
APOSBISN0101-1G
APOSBISN0101-5G
N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
Gefitinibis an EGFR inhibitor for Tyr1173, Tyr992, Tyr1173 and Tyr992 in the NR6wtEGFR and NR6W cells with IC50 of 37 nM, 37nM, 26 nM and 57 nM, respectively, and interrupts signaling through the epidermal growth factor receptor (EGFR) in target cells.
Formel:
C₂₂H₂₄ClFN₄O₃ MW: 446,91 g/mol Smältpunkt: 196 °C Storage Temperature: Kylskåp |
MDL Number:
MFCD04307832 CAS nummer: 184475-35-2 |
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