DNA/RNA oxidative damage (high sensitivity) ELISA kit

Leverantör: Cayman Chemical

589320-480 589320-96 589320-96S 589320-480S
CAYM589320-480EA 60600 SEK
CAYM589320-480 CAYM589320-96 CAYM589320-96S CAYM589320-480S
DNA/RNA oxidative damage (high sensitivity) ELISA kit
Analyser ELISAs

A competitive ELISA that can be used to measure 8-OHdG, 8-OHG, and 8-hydroxyguanine resulting from DNA/RNA oxidative damage.


DNA and RNA are damaged by oxidation during aging and in a variety of disease states including cancer. Guanine is the base is most prone to oxidation, and the repair processes initiated to correct the damage release multiple oxidised guanine species into the urine, including 8-hydroxyguanosine (8-OHG), 8-hydroxy-2’-deoxyguanosine (8-OHdG), and 8-hydroxyguanine. Some commercial vendors offer immunoassays that detect only 8-OHdG. Cayman's DNA/RNA Oxidative Damage (High Sensitivity) ELISA Kit is a competitive assay that can be used to measure 8-OHdG, 8-OHG, and 8-hydroxyguanine. Since the antibody used in the assay recognises damaged nucleic acid species other than 8-OHdG, the value obtained with our assay will be higher than that obtained by competitor ELISAs or by LC/MS analysis that measure a single species. As such, caution is recommended when comparing results obtained from this kit to those obtained by other methods.


Observera: This product is not for human or veterinary use.

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