Ricobendazole ≥98%
Leverantör: Cayman Chemical
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Varning
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Synonyms:
Albendazole sulphoxide, N-[6-(propylsulphinyl)-1H-benzimidazol-2-yl]-carbamic acid, methyl ester, Albendazole Oxide, Methyl (6-(propylsulphinyl)-1H-benzo[d]imidazol-2-yl)carbamate
Ricobendazole, also known as albendazole sulfate, is a benzimidazole agent that inhibits tubulin polymerization and is commonly used as an antihelmintic and antiparasitic agent, with IC90 values ranging from 3.8 x 10-2 to <10-4 µg/ml against Encephalitozoon species.
- Formulation: A crystalline solid
- λmax: 224, 294 nm
In vitro, ricobendazole effectively kills Taenia cysts, with EC50 and EC99 values of 0.068 and 0.556 µg/ml, respectively, in 11-day cultures, and inhibits adherence in Giardia species with a 24-hour IC50 value of 3.15 µM.5,6 This agent is metabolized from albendazole via cytochrome P450 (CYP450) and may modulate CYP450 activity. In rat microsomes, ricobendazole reduces the activity of ethoxyresorufin O-deethylase (EROD) by more than 5-fold relative to albendazole, with an IC50 value of 5 µM.
Formel:
C₁₂H₁₅N₃O₃S MW: 281,3 g/mol Storage Temperature: Frys |
MDL Number:
MFCD00797922 CAS nummer: 54029-12-8 |
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