Apixaban ≥98%, crystalline solid

Leverantör: Cayman Chemical
Fara

Synonyms: BMS56224701, 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5-dihydropyrazolo[5,4-c]pyridine-3-carboxamide, 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide

15427-10 15427-5 15427-1 15427-50
CAYM15427-10EA 10250 SEK
CAYM15427-10 CAYM15427-5 CAYM15427-1 CAYM15427-50
Apixaban ≥98%, crystalline solid
Apixaban

Apixaban is an orally bioavailable, selective inhibitor of both free and prothrombinase-bound factor Xa (Kis = 0.8 nM).


In vivo, apixaban has antithrombotic effects in a rabbit model of venous thrombosis. Apixaban (357.5 mg) also prevents thrombus formation without inducing adverse bleeding events in a porcine model of aortic heterotopic valve replacement. Formulations containing apixaban have been used to prevent blood clot formation in patients with atrial fibrillation.

Formel: C₂₅H₂₅N₅O₄
MW: 459,5 g/mol
Storage Temperature: Frys
MDL Number: MFCD11977295
CAS nummer: 503612-47-3

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Specifikation testresultat

Purity ≥98%
λmax (UV/Vis) 281 nm

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