3,3'-Di-n-hexyloxacarbocyanine iodide [DiOC6(3) iodide] ≥98%, crystalline solid
Leverantör: Cayman Chemical
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Varning
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Synonyms:
3-Hexyl-2-[3-(3-hexyl-1,3-benzoxazol-2(3H)-ylidene)-1-propen-1-yl]-1,3-benzoxazol-3-ium iodide, DiOC6(3) iodide, DiOC6(3), 3,3'-Dihexyloxacarbocyanine iodide, 3-Hexyl-2-[3-(3-hexyl-2(3H)benzoxazolylidene)-1-propenyl]benzoxazolium iodide
3,3'-Dihexyloxacarbocyanine (DiOC₆(3)) is a lipophilic fluorescent dye with excitation/emission spectra of 484/501 nm, respectively.
At high concentrations, DiOC₆(3) accumulates in the endoplasmic reticulum (ER) and has been used to visualise ER in moss, yeast, and muscle cells. At low concentrations, DiOC₆(3) accumulates in mitochondria and has been used to assess mitochondrial dislocations, fusion, and fission in living cells, as well as to visualize cellular apoptosis.
DiOC₆(3) can also be used to assess cell membrane potential, as depolarisation directly correlates with increased fluorescence.2,3 DiOC₆(3) photoexcitation inactivates intracellular organelle movement and inhibits microtubule polymerisation in-vitro.
Formel:
C₂₉H₃₇IN₂O₂ MW: 572,531 g/mol Storage Temperature: Frys |
MDL Number:
MFCD00011954 CAS nummer: 53213-82-4 |
Specifikation testresultat
Purity | ≥98% |
Emission | 501 nm |
Excitation | 484 nm |
λmax | 486 nm |
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