Hydroxy-2-naphthalenylmethylphosphonic acid ≥95%, crystalline solid
Leverantör: Cayman Chemical
Synonyms:
HNMPA
15543-1
15543-10
15543-25
15543-5
CAYM15543-1EA
935
SEK
CAYM15543-1
CAYM15543-10
CAYM15543-25
CAYM15543-5
Hydroxy-2-naphthalenylmethylphosphonic acid ≥95%, crystalline solid
Hydroxy-2-naphthalenylmethylphosphonic acid
HNMPA is a cell impermeable tyrosine kinase inhibitor that blocks receptor serine and tyrosine phosphorylation, including insulin receptor tyrosine kinase activity.
It does not affect protein kinase C or cyclic AMP-dependent protein kinase activities. HNMPA inhibits the insulin-stimulated autophosphorylation of the 95 kDa β-subunit of the insulin receptor with an IC50 value of 200 µM in-vitro.
Formel:
C₁₁H₁₁O₄P MW: 238,2 g/mol Storage Temperature: Frys |
CAS nummer:
132541-52-7 |
Specifikation testresultat
Purity | ≥95% |
λmax | 228 nm |
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