Alum adjuvant, AlumVax hydroxide

Leverantör: OZ BIOSCIENCES

AH0050 AH0250
OZBIAH0050EA 1350 SEK
OZBIAH0050 OZBIAH0250
Alum adjuvant, AlumVax hydroxide
Proteinexpressions Reagens för proteinexpression

AlumVax hydroxide is a wet gel (colloidal) of aluminium hydroxide 2%. It is the most common adjuvant used in approved prophylactic vaccines because of its excellent safety profile and ability to enhance the protective humoral immune response.


  • Ready to use suspension
  • Store at room temperature


It has been observed that aluminium compounds act by a depot effect and also by direct activation of the immune cells. Adsorption or entrapment of antigens in aggregates through hydrophobic and electrostatic interactions favours a high local antigen concentration and improved uptake by antigen presentating cells (APC).


AlumVax hydroxide is a crystalline aluminium oxyhydroxide that is positively charged at physiological pH (pI=11), suitable for adsorption of negatively charged, acidic proteins (such as albumin). It stimulates Th2 response through the release of Th2-associated cytokines (IL4, IL-5, IL-13) and Th2-associated antibodies (IgG1 and IgE). It increases Ag-specific CD4+ T Cell proliferation and promotes NALP3 inflammasome activation and caspase 1-mediated release of IL-1 and IL-18.


Leveransinformation: Shipped at room temperature.


Observera: Intended for research use only.

Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Läs mer About VWR