Tenofovir disoproxil fumarate ≥98%, crystalline solid

Leverantör: Cayman Chemical
Fara

Synonyms: (R)-(((((1-(6-Amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphoryl)bis(oxy))bis(methylene) diisopropyl dicarbonate fumarate

16922-10 16922-25 16922-5 16922-50
CAYM16922-10EA 3150 SEK
CAYM16922-10 CAYM16922-25 CAYM16922-5 CAYM16922-50
Tenofovir disoproxil fumarate ≥98%, crystalline solid
Tenofovir disoproxil fumarate

Tenofovir disoproxil is a prodrug of the acyclic nucleoside phosphonate, tenofovir. Tenofovir is converted by cellular enzymes to tenofovir diphosphate, an obligate chain terminator that inhibits the activity of HIV reverse transcriptase and hepatitis B virus polymerase. Due to its rapid intracellular uptake, the anti-HIV activity of tenofovir disoproxil is reportedly >100-fold greater than that of the negatively charged tenofovir in a T cell line and primary blood lymphocytes.


  • Crystalline solid
  • Soluble in organic solvents such as ethanol, DMSO and dimethyl formamide (DMF)
  • Sparingly soluble in aqueous buffers

Formel: C₁₉H₃₀N₅O₁₀P·C₄H₄O₄
MW: 635,5 g/mol
Storage Temperature: Frys
MDL Number: MFCD08141829
CAS nummer: 202138-50-9

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