D,L-Anatabine ≥95% i etanol
Leverantör: Cayman Chemical
Synonyms:
1,2,3,6-Tetrahydro-2,3'-bipyridine, (R,S)-Anatabine
(R,S)-Anatabine is a minor alkaloid produced in plants of the Solanaceae family, including tobacco.
The detection of (R,S)-anatabine in urine is used as an indicator of tobacco use, particularly when nicotine-containing products (gum, patches, inhalers, and medications) are also being used. (R,S)-Anatabine increases nicotine self-administration and locomotor activity in rats. Of note, (R,S)-anatabine diminishes amyloid beta (Aβ) production in vitro and in vivo. (R,S)-Anatabine reduces (600 µg/ml) the transcription and protein levels of β-secretase, lowering the amount of Aβ1-40 and Aβ1-42 in a dose dependent manner in SHSY-5Y cells. (R,S)-Anatabine also dose dependently inhibits NF-κB activation.
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Formel:
C₁₀H₁₂N₂ MW: 160,22 g/mol |
MDL Number:
MFCD00078278 CAS nummer: 2743-90-0 |
Specifikation testresultat
| Purity | ≥95% |
| Formal Name | 1,2,3,6-tetrahydro-2,3'-bipyridine |
| Formulation | A solution in Ethanol |
| λmax | 261 nm |
| SMILES | [C@@H]1(C2=CN=CC=C2)CC=CCN1 |
| InChI Code | 1S/C10H12N2/c1-2-7-12-10(5-1)9-4-3-6-11-8-9/h1-4,6,8,10,12H,5,7H2 |
| InChI Key | SOPPBXUYQGUQHE-UHFFFAOYSA-N |
| Storage | −20 °C |
| Shipping | Wet ice in continental US; may vary elsewhere |
| Stability | 1 year from the QC date provided on the Certificate of Analysis, when stored properly |
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