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Mycoplasma: Detection & Elimination Mycoplasma in Cell Culture Contamination of cell lines with mycoplasma is a widespread and often underestimated problem. Although visible signs like turbidity or pH-changes are rare mycoplasma infections can cau...

Contamination Prevention & Detection Featured Solutions PanReac AppliChem offers a variety of solutions for prevention detection and fighting against cell culture contamination. Mycoplasma: detection & elimination Antibiotics & Antimycotics Additi...

product information 1 PCR Mycoplasma Test Kit Ready-to-use PCR Mix for the detection of Mycoplasma in Cell Culture Product-No. A3744 Introduction The PCR Mycoplasma Test Kit is designed to detect the presence of Mycoplasma contaminating biological...

Downstream purification for gene therapy With more than 30 years of chromatography experience developed products and services we have every solution to meet your needs. Our J.T.Baker® brand BAKERBOND™ chromatography resins have been used successfu...

Final fill for cell therapy The cell therapy drug product is configured in different ways depending on the required delivery of the cells/tissues. For example delivery of chondrocytes for cartilage repair is administered by an injection. Expanded ...

Downstream purification for recombinant proteins With more than 30 years of chromatography experience developed products and services we have every solution to meet your needs. Our J.T.Baker® brand BAKERBOND™ chromatography resins have been used s...

Final fill for mAbs Progressing from the drug substance to the final injectable drug product requires final packaging vials and stoppers that meet a number of quality requirements. To meet these requirements products must be prepared in an ISO Cla...

Final fill for vaccines Progressing from the drug substance to the final injectable drug product requires final packaging vials and stoppers that meet a number of quality requirements. To meet these requirements products must be prepared in an ISO...

PanReac Applichem Decontamination Decontamination and Control Reagents It is important to work clean as contamination is very frustrating for the scientist and in the end also very expensive. PanReac AppliChem offers a variety of products for prev...

Downstream purification for vaccines During subsequent steps for vaccine concentration and clarification followed by passage through several filtration steps and chromatography columns it is critical that vaccine purity potency and consistency be ...

Upstream processing for cell therapy Compared to production volumes associated with other biologics (e.g. mAbs: 2000L to 10000L) cell therapy production volumes are more commonly between 1L to 10L. Even the quality parameters are different. Instea...

Upstream processing for mAbs Developing and manufacturing mAbs has moved away from a dependency on raw materials of animal origin. Our biochemical components and supplements are animal component-free to meet the needs of these applications. Produc...

Upstream processing for microbial-based recombinant proteins Using microbial fermentation for the development and manufacture of recombinant proteins keeps on showing advantages e.g for the expression of proteins that do not require post-translati...

Downstream purification for mAbs Major processes including affinity ion exchange HIC and size exclusion require chromatography resins and process buffers. These products help ensure that the quality of the target mAb is maintained through each ste...

Upstream processing for vaccines Optimal production of vaccines is achieved in mammalian expression and insect systems using cell lines that are anchorage-dependent or suspension enabled. For most vaccines optimal production is achieved in mammali...

infoPoint Surveys of cultures from labs all over the world reveal a strong prevalence of contamination by Mycoplasma and other Mollicutes. Depending on the method of detection 10-40% of continuous cell lines have been tested positively. The specie...